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Formation Bio

General Manager (Drug Asset Lead)

Formation Bio
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hybrid executive full-time $311,000 - $388,500 New York, Boston, NY, MA

First indexed 18 Jun 2026

Description

We are seeking a General Manager to lead a Formation Bio asset, responsible for translating the investment thesis into action and progressing the asset towards value inflection with speed, efficiency, and leverage. The ideal candidate will own the asset strategy, budget, and execution rhythm, ensuring momentum, clarity, and disciplined delivery across functions. This role requires a high degree of autonomy, accountability, and decision-making.

Responsibilities:

  • Refine and deliver the strategy for the asset and define key results that ladder up to asset objectives.
  • Drive and own business outcomes, including asset P&L, budgets, ROI, and value inflection with speed.
  • Lead a team of full-time and contract team members, forecasting and pulling resources as needed.
  • Partner with the assigned Tech Lead, Clinical Development Lead, and other functional subject matter experts to drive asset strategy and execution.
  • Establish and run team rituals that ensure clarity, accountability, and disciplined execution.
  • Anticipate and surface tradeoffs, risks, and governance needs, while maintaining autonomy for operational decisions.
  • Develop and maintain comprehensive governance tools, such as asset development roadmaps, registers, and dashboards.
  • Track and manage against success metrics, including milestone adherence, team efficiency, and overall asset value.
  • Provide ongoing strategic updates to the Formation Bio Leadership Team, ensuring alignment with broader portfolio and company-level strategy.

Requirements:

  • Outcome-Driven: You optimise for value creation and speed, not process for its own sake.
  • Radically Accountable: You own timelines, budgets, risks, and tradeoffs without relying on matrix ambiguity.
  • AI-Native: You naturally embed AI and automation into team culture, workflows, and decisions.
  • Generalist With Range: You flex across disciplines, knowing when to go deep or bring in expertise and when to rely on the team.
  • Influential Without Authority: You earn trust and alignment among SMEs and functional leaders without direct reporting lines.
  • Structured & Decisive: You run the team like a business,with sharp prioritization, clear charters, and disciplined execution.
  • Comfortable in Ambiguity: You thrive in dynamic environments, simplify complexity, and adapt quickly.
  • Strategically grounded with tactical depth: You seamlessly connect high-level vision to detailed, practical action.

Total Compensation Range: $311,000 - $388,500

In addition to base salary, we offer equity, comprehensive benefits, and generous perks. We are prioritising hiring in key hubs, primarily the New York City and Boston metro areas, with a hybrid model requiring 3 days per week in office. Applicants from the Research Triangle (NC) and San Francisco Bay Area may also be considered.

This listing is enriched and indexed by YubHub. To apply, use the employer's original posting: https://job-boards.greenhouse.io/formationbio/jobs/7383481