Description
We are seeking an exceptional and highly experienced individual for a position as Director/Senior Director of Antibody Discovery. This individual will lead our antibody discovery and display function, conceiving of and leading multi-year team and technology strategy as well as managing routine operational execution for identification and maturation of high-quality antibodies across antigen types for both BigHat and BigHat-partnered therapeutic research programs.
Key Responsibilities:
- Lead BigHat's antibody discovery and display functions, setting the scientific, technical, and strategic direction
- Oversee the routine execution of display-based selection campaigns to enhance and diversify affinity, developability, and function across diverse antibody formats and antigen types in support of BigHat and BigHat-partnered therapeutic programs
- Manage and mentor a team of scientists responsible for antibody library design, generation, screening, selection, and early optimization
- Shape and expand BigHat's antibody discovery technologies and capabilities, including new display and selection methods, library design strategies, and technical approaches that leverage and enhance the company's integrated experimental and computational platform
- Provide scientific leadership across discovery and early optimization efforts, ensuring antibodies emerging from selections possess strong functional and developability characteristics
- Work closely with leaders in Protein Sciences, Data Science/Machine Learning, Engineering, and Platform groups to ensure seamless progression from discovery through characterization and optimization
- Collaborate with biology and therapeutic research leads to ensure display outputs align with and advance program objectives
- Foster a collaborative and high-performance culture within the discovery organization
Benefits: The salary estimated for this position is $230,000 - $270,000 + bonus + options + benefits. Compensation will vary depending on job-related knowledge, skills, and experience. Actual compensation will be confirmed in writing at the time of the offer.
We offer a range of health insurance plan options through Anthem and Kaiser, dental and vision coverage through Guardian, additional well-being benefits through Nayya, OneMedical, Wagmo, Rula, and more, 401(k) with company match, DTO, two weeks of company-wide shutdown, and 12 company holidays, paid parental leave.