Global BPM CVRM Weight Management/Obesity

Senior Global Medical Affairs Leader, Obesity

Global BPM CVRM Weight Management/Obesity
onsite senior full-time Boston, Massachusetts, United States of America
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First indexed 18 Apr 2026

Description

Are you ready to be at the forefront of medical innovation? As the Senior Global Medical Affairs Leader for Obesity and Related Complications, you'll play a pivotal role in shaping the future of obesity care. This is your chance to use your expertise to make a real impact on patients' lives.

In this dynamic role, you'll be responsible for providing medical leadership across the entire product lifecycle. You'll advise on Research & Development investment decisions, lead pre-launch scientific efforts, and accelerate evidence-based healthcare changes in the real world. Your networking and influencing skills will be key as you facilitate cross-functional collaboration and drive innovation.

Reporting to the Medical Head of Weight Management, the Senior GMAL is a highly experienced Medical Affairs leader with proven vision and impact. This individual develops and leads bold medical strategies within the obesity and cardiorenal-metabolic outcomes therapy area (specifically MASH, heart failure and CKD), expertly guiding cross-functional and cross-regional teams to deliver and exceed ambitious goals.

The Senior GMAL's influence is enterprise-wide,shaping global medical agendas through Global Medical Team, Global Product Team, and Disease Area Team leadership, and deep partnership with Medical and Commercial functions in markets and regions worldwide. This role demands a leader who champions innovative, disruptive thinking,identifies and shapes breakthrough opportunities, reimagines market dynamics, and accelerates high-impact evidence generation and medical change initiatives.

Key responsibilities include: Strategy & Transformation: Design and lead the implementation of product and disease area strategies, as well as ambitious practice change initiatives, at a global level. Medical Evidence Leadership: Own the evidence generation strategy, demonstrating advanced experience in clinical research, interventional trials (Phases 2–4), and real-world evidence (RWE) programs. Advanced Scientific & Digital Engagement: Blend scientific expertise with strong digital acumen, leveraging digital health tools, advanced analytics, and data platforms to transform evidence communication, personalize stakeholder engagement, and enhance patient outcomes. Guiding and Influencing Stakeholders: Build and sustain powerful relationships across the healthcare ecosystem, including global and regional KOLs, professional societies, regulators, payers, patient organizations, digital innovators, and health systems. Regulatory Insight & Compliance: Possess keen regulatory understanding and ensure clinical trial and evidence generation initiatives are designed for both scientific and regulatory success.

Essential qualifications include: Doctoral-level degree (MD, PhD, PharmD) Master’s degree with at least 5 years of experience in the pharmaceutical industry (Medical, Marketing, R&D, Market Access), or extensive experience within a health system (clinical, pharmacy, pathway design, etc.) Demonstrated leadership in complex, global healthcare environments, including leading franchise/TA business in key markets, driving brand performance, and managing large, diverse teams. Significant expertise and strategic insight into healthcare system pathways, regulatory landscapes, market-shaping, and external stakeholder engagement. Strong track record of internal and external network building, collaboration across geographies and matrix teams, and effective mentoring of junior colleagues or peers. Digital proficiency, leveraging digital health tools and data platforms to advance evidence generation and communication. Deep understanding of patient care pathways, evolving treatment protocols, scientific literature, and contemporary approaches to healthcare transformation. Proven ability to guide, influence, and align diverse stakeholders,including thought leaders, regulatory bodies, patient groups, and payer organisations.

Desirable qualifications include: Clinical experience in obesity, PCP, heart failure and/or CKD Experience with the USA health care system Recognised expertise in the relevant or related therapeutic area, often evidenced by a history of clinical practice, research leadership, or significant external engagement. Advanced experience designing, leading, and interpreting clinical research programs, including pivotal clinical trials (Ph2–Ph4), practice-changing RWE studies, and implementation of innovative evidence generation approaches. Broad experience beyond Medical Affairs; for example, prior roles in Marketing, R&D, or Market Access. Long-standing relationships with global KOLs, societies, regulators, digital health partners, and innovative healthcare organisations. Track record of launching new products or indications in multiple, diverse markets (e.g., US, China, EU), and successfully developing and executing global medical strategies.

Total Rewards: The annual base pay (or hourly rate of compensation) for this position ranges from $243,586 to $365,379. Our positions offer eligibility for various incentives,an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement plans.

This listing is enriched and indexed by YubHub. To apply, use the employer's original posting: https://astrazeneca.eightfold.ai/careers/job/563877689883777