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From the employer's careers site First seen 31 Oct 2026 · Still live on 9 Nov 2026

VP, Program Management & Business Operations

Alltrna Cambridge, MA executive full-time

Salary

$250,000 - $330,000 per year

Apply on Alltrna

Description

Alltrna is seeking a talented and highly motivated VP, Program Management and Business Operations, reporting to the President & CFO.

The successful candidate is a proven leader with extensive experience in leading research and early drug development program teams from research through the clinic with a particular initial focus on IND enabling and early/mid-stage clinical development.

Key Responsibilities:

Program Management:

  • Work closely with the Chief Medical Officer to lead the program team for the Company’s lead program, AP003, and future programs instilling a culture of scientific rigor, open debate, collaborative teamwork, sense of urgency and accountability
  • Possess a comprehensive understanding of the drug discovery process to guide program teams to define the key scientific questions, program strategy and objectives, translating these into optimal deliverables, cross-functional plans, timelines and budgets
  • Identify bottlenecks, risks, issues and proactively develop appropriate mitigation proposals with input from team members
  • Ensure all key decisions are identified and properly assessed as to their impact and alternative scenarios developed and evaluated, where appropriate
  • Work closely with finance and functional teams to develop the operational plans to support program activities with realistic timelines, budget, and resource planning and monitor performance against plans
  • Interface with and drive collaboration between the various functional teams and with the Leadership Team on program-related matters
  • Be the key accountable person for communicating matters related to the programs to management including strategy, work product, updates and issues; producing the one “source of truth” for program-related topics and timelines
  • Point person for alliance management and coordination, as needed
  • Lead and/or manage strategic or platform development projects as required and collaborate with Chief Scientific Officer and Research Leadership Team to coordinate relevant content for quarterly business review meetings

Operations:

  • Collaborate with Leadership Team in development of strategic plans, company goals, long-range planning assumptions, portfolio-level reports and analyses to support business processes and strategic discussions
  • Develop and deliver impactful presentations that effectively distill complex issues to the critical points and lead to increased understanding and optimized strategic planning & decision-making
  • Prepare strategic communications utilizing a clear understanding of the business strategy and issues; develop and maintain consistent, relevant content for use in executive-level communications and to further organizational and business goals
  • Lead the Scientific Communications process, working with the Scientific Communications Committee
  • Manage schedule, agenda, and content for Leadership Team, Board of Directors and Town Hall meetings
  • Proactively seek opportunities for organizational improvements (e.g. team structure, processes, communication, etc.)

Other:

  • Support CEO / LT with partnership discussions and negotiations, including background research, preparation of presentation materials, supporting diligence activities, participating in analysis of terms, etc.
  • Assist in mapping competitive landscape and proactively identify potential and emerging competitive threats and opportunities
  • Promote strategic discussions on external trends, competitor strategies, and potential disruptors, and translate these into strategic choices/ recommendations
  • Collect insights and intelligence from a variety of sources including literature searches, reviewing analyst research, KOL and patient group interactions, etc.

Key Competencies:

  • Exceptional interpersonal and communication skills, creative thinking, and early drug development experience
  • Self-confidence and poise to manage complicated programs and projects with multiple stakeholders
  • Sense of urgency and can-do attitude to develop therapies for patients with significant unmet medical needs

Minimum Qualifications:

  • BS/MS Degree in a scientific discipline, ideally life science or chemistry
  • At least 15 years relevant experience in pharma or biotech drug discovery and development
  • 10+ years of Program Management experience, preferably in early-stage drug discovery and development
  • Experience in the development of advanced therapies to treat rare genetic disease is a plus
  • Demonstrated experience leading cross-functional teams; strong interpersonal and communication skills
  • Scientific curiosity and passion for discovering new, innovative medicines
  • Openness to embrace new technologies and digital approaches in drug discovery
  • Proven track record in driving successful, collaborative drug discovery teams

The salary range for this role is $250,000 - $330,000. Compensation for the role will depend on a number of factors, including a candidate's qualifications, skills, competencies, and experience. Alltrna currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits.

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Skills

Required

Nice to have

  • advanced therapies
  • rare genetic disease
  • tRNA medicines

Ready to apply?

You apply with the employer directly. Their original posting is here: https://job-boards.greenhouse.io/flagshippioneeringinc/jobs/8520490002

Apply on Alltrna