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From the employer's careers site First seen 10 Nov 2026

Senior Scientist, Upstream Processing

GSK Pennsylvania - King of Prussia On-site senior full-time

The employer hasn't listed a salary.

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Description

Join us as a Senior Scientist, Upstream Processing and play a key role in advancing scientific research that makes a real difference. You will work closely with diverse teams to design, carry out, and analyze experiments. Your insights will help shape innovative solutions that align with our mission to unite science, technology, and talent to get ahead of disease together.

We value curious, motivated scientists who take ownership, communicate clearly, and thrive in a collaborative environment. This role offers you a chance to grow your skills, make a meaningful impact, and contribute to GSK’s mission.

Responsibilities:

  • Leads the manufacture of clinical supply of investigational biopharmaceutical molecules, including hands-on cGMP large scale cell culture for use in early phase clinical trials
  • Leads or works on projects and assignments where independent action and a high degree of initiative and knowledge are required for execution or to provide recommendations
  • Supports the technology transfer process through active participation in ensuring that new processes fit and execute consistently
  • Troubleshoots problems in the execution of processing activities; proactively assesses options and impact and takes action to rectify or communicate to appropriate decision makers
  • Identifies process improvement opportunities with impact on safety, compliance, and efficiency/cost
  • Maintains and performs compliance checks for documentation in logs, media forms, batch records, and electronic systems in accordance with company policy and legal requirements
  • Strives for Right First Time in the manufacture of investigational material through attention, focus, planning, and adherence to procedural and regulatory expectations

Basic Qualifications:

  • BS, MS, or PhD in Chemical Engineering, Biology, Chemistry, or other engineering or scientific field
  • A minimum of 3 years of direct GMP manufacturing experience or upstream processing experience in a biotechnology manufacturing facility or Pilot Plant

Preferred Qualifications:

  • Thorough knowledge of Good Manufacturing Practices (GMP) regulations
  • Demonstrates good interpersonal skills and communicates well both verbally and through written communications
  • Maintains a professional and productive relationship with area management and co-workers
  • Thorough knowledge of routine laboratory/plant equipment and demonstrates high level of technical expertise with working familiarity with several methods, techniques, laboratory procedures and processes
  • Possess in-depth knowledge of how to analyze and interpret experimental/process data

Benefits: We offer a competitive salary, an annual bonus based on company performance, healthcare and wellbeing programs, pension plan membership, and shares and savings programme. We also offer a remote or hybrid working model through our Performance with Choice programme.

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Skills

Required

  • Chemical Engineering
  • Biology
  • Chemistry
  • GMP manufacturing
  • upstream processing

Nice to have

  • Good Manufacturing Practices (GMP) regulations
  • interpersonal skills
  • laboratory/plant equipment
  • experimental/process data analysis
Apply on GSK