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From the employer's careers site First seen 28 Oct 2026

Operating Principal, Summit PBU

Salary

$220,000 - $269,500 per year

Apply on Flagship Pioneering

Description

Summit, a Pioneering Business Unit within Flagship, is seeking an Operating Principal to help launch and scale our NewCos.

You will work across one or more companies, leading operations and strategy, driving corporate development, and partnering closely with scientific leadership to translate breakthrough ideas into impact.

This role is ideal for an entrepreneurial leader who thrives in ambiguity, moves seamlessly between science and business, and is energized by building organisations from inception to growth.

Key Responsibilities

  • Lead strategy and operational planning in one or more NewCos.
  • Drive corporate development initiatives, including partnerships, financings, and strategic alliances, as well as engagement with Board of Directors and other important stakeholders.
  • Engage directly with scientists and company leaders to align technical progress with operational goals.
  • Recruit, develop, and manage high-performing teams across functions.
  • Partner with Flagship central teams (Finance, Talent, Legal/IP, HR) to bring best-in-class infrastructure to each company.
  • Shape and execute operating and long-range plans, ensuring milestones are achieved on time and on budget.
  • Build strong external relationships with investors, partners, and key opinion leaders.

Professional Experience & Qualifications

  • 10+ years of experience in biotech, pharma, or life sciences strategy/operations; prior management consulting a plus.
  • Proven success in strategic, operational, or corporate development leadership, ideally in early-stage biotech.
  • Strong scientific acumen; able to quickly grasp novel science and translate it into plans and execution.
  • Track record of building and motivating high-performing teams.
  • Skilled communicator, able to influence and inspire across investors, partners, and internal teams.
  • Expert problem solver; can bring order to chaos and iterate quickly to find solutions.
  • Entrepreneurial, resilient, and hands-on; able to adapt and execute with urgency; doesn’t mind rolling up sleeves and doing what needs to be done to move the ball forward.

Education

  • Advanced degree in life sciences or business preferred (PhD, MD, MBA, or equivalent experience).

Benefits

  • Healthcare coverage
  • Annual incentive program
  • Retirement benefits
  • Broad range of other benefits

Skills

Required

Nice to have

Ready to apply?

You apply with the employer directly. Their original posting is here: https://job-boards.greenhouse.io/flagshippioneeringinc/jobs/8175032002

Apply on Flagship Pioneering