Description
Hims & Hers is the leading health and wellness platform, on a mission to help the world feel great through the power of better health.
The Production Chemist performs hands-on cGMP peptide manufacturing, supporting either upstream operations (synthesis and cleavage) or downstream operations (preparative HPLC purification and lyophilization).
Responsibilities:
- Execute assigned manufacturing tasks per approved batch records, SOPs, and work instructions with minimal supervision, in a timely and efficient manner.
- Perform SPPS and cleavage operations, including resin preparation, synthesizer operation, cleavage, precipitation, and crude peptide isolation.
- Verify protected amino acids batch by batch against specification, including solubility and appearance, before use.
- Perform prep HPLC purification, fraction pooling, concentration, lyophilization, and final packaging.
- Check analytical HPLC and mass of dissolved crude peptide and identify the target peptide peak by integration and mass spectrometry to guide purification and fraction pooling.
- Handle raw materials, solvents, and reagents safely; operate and clean production equipment and instruments.
- Prepare and label chemical solutions and buffers according to standard formulas.
- Perform in-process checks and escalate unexpected results right away.
- Complete batch records, logbooks, and standardized forms accurately and in real time.
- Review data for accuracy and completeness before submission and perform data analysis as assigned.
- Report deviations promptly, keep the work area clean, organized, and inspection-ready, and complete GMP and safety training on time.
- Work closely with teammates, Quality, QC, and Maintenance, and take part in cross-training.
Requirements:
- Bachelor’s degree in chemistry, Biochemistry, Chemical Engineering, or a related discipline.
- Hands-on laboratory experience, through coursework, internships, or work.
- Strong attention to detail and the ability to follow procedures precisely and document accurately.
- Strong communication and time management skills, and ability to work independently and as part of a fast-moving team.
- Ability to stand for extended periods, lift up to 40 lbs., and wear required PPE.
Preferred Qualifications:
- Background or hands-on experience in peptide synthesis (SPPS), from academic research, an internship, or industry (upstream).
- Experience with HPLC purification or lyophilization (downstream).
- Familiarity with analytical HPLC and mass spectrometry for in-process data review.
- Prior exposure to cGMP or regulated environments.
Benefits:
- Competitive salary & comprehensive health benefits including medical, dental & vision.