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From the employer's careers site First seen 5 Nov 2026

Sr Director Therapeutic Area (Hepatology)- US- Remote

ICON plc Cambridge, MA Remote senior full-time

Salary

$195,808-$244,760 per year

Apply on ICON plc

Description

ICON is seeking a Senior Director, Drug Development & Consulting – Cardiometabolic to join their team in a highly visible, client-facing role.

This position offers the opportunity to act as a trusted advisor to senior stakeholders across the industry, including CEOs, CMOs, and other Cardiometabolic Therapeutic Area Heads.

The Role

This is a consultative and advisory role where you will serve as a key scientific partner to both external clients and internal teams.

Key Responsibilities

  • Lead strategic Cardiometabolic drug development design, delivering tailored, asset-focused solutions across liver diseases including MASLD/MASH, alcohol-associated liver disease (ALD), cirrhosis, viral hepatitis, and other chronic and rare liver conditions like PBC, PSC, PFIC
  • Own end-to-end protocol development, including design, scientific review, and evaluation for Cardiometabolic clinical trials across Phases I–IV
  • Partner directly with senior client stakeholders (e.g., CMO, TA Heads, Clinical Development leadership) to provide expert guidance on Cardiometabolic development strategy and data interpretation
  • Act as scientific and strategic lead in proposal development, study strategy, and bid defense activities within Cardiometabolic
  • Build and maintain strong relationships with Cardiometabolic key opinion leaders (KOLs), advisory boards, and relevant regulatory authorities
  • Contribute to the development of Cardiometabolic-focused service offerings, supporting innovation and growth in liver disease drug development capabilities
  • Provide training, mentorship, and thought leadership in Cardiometabolic to internal teams and external partners
  • Participate in portfolio reviews, governance discussions, and scientific oversight of Cardiometabolic programs
  • Support operational teams with high-level scientific input, including investigator meetings and Cardiometabolic-specific study discussions
  • Represent the organization at Cardiometabolic congresses and scientific forums to promote clinical excellence and scientific leadership

What You Bring

  • Deep, recognized expertise in Cardiometabolic and liver disease drug development
  • Strong understanding of Cardiometabolic clinical trial design, biomarkers, endpoints (e.g., fibrosis staging, histologic and non-invasive markers), and evolving therapeutic landscapes (e.g., MASLD/MASH, alcohol-associated liver disease (ALD), cirrhosis, immuno-Cardiometabolic approaches and antiviral therapies)
  • Proven ability to operate in a strategic, client-facing, consultative environment within pharmaceutical or clinical research settings
  • Experience engaging and influencing senior scientific and clinical stakeholders across industry and academia
  • Excellent communication and presentation skills, with the ability to translate complex Cardiometabolic data into clear, actionable development insights
  • Collaborative, global mindset with strong cross-functional leadership capability
  • MD required, ideally with specialization or substantial clinical/research experience in Cardiometabolic diseases

Additional Information

  • 20- 40% travel (domestic and international)
  • Opportunity to work in a highly visible, impact-driven role shaping the future of Cardiometabolic drug development

Rewards & Benefits

  • Competitive base salary and performance related incentives
  • Health and wellbeing programmes including medical, dental, and vision coverage where applicable
  • Retirement and pension plans
  • Life assurance and disability coverage
  • Employee assistance programmes and wellbeing resources
  • Learning and development opportunities through structured training and career pathways

Skills

Required

  • Cardiometabolic
  • liver disease
  • drug development
  • clinical trials
  • scientific leadership
Apply on ICON plc