Description
We are seeking a highly motivated and exceptionally organized Research Associate II to expand our protein production capabilities across two complementary scales: bulk expression and purification of individual high-priority targets, and high-throughput parallel production of large variant panels.
This hands-on, laboratory-facing role will execute and advance scalable protein expression, purification, normalization, and characterization workflows that feed the design–build–test cycles at the core of our platform.
Key Responsibilities:
- Bulk Expression & Purification: Execute multi-liter recombinant expression campaigns in bacteria, design, build, and run preparative purification methods on ÄKTA FPLC systems, deliver milligram-to-gram quantities of highly pure, well-characterized protein.
- High-Throughput Production & Analytics: Execute miniaturized, parallel protein expression and purification in plate-based formats, perform automated purification, sample normalization, and quality assessment to deliver fit-for-purpose protein reagents at scale.
Required Qualifications & Experience:
- Bachelor’s degree in biochemistry, molecular biology, biotechnology, bioengineering, synthetic biology or a related scientific discipline with 1-4 years of relevant academic and/or industry experience; or a master’s degree with 0-2 years of commercial experience.
- Hands-on experience with recombinant protein expression and production workflows in E. coli, including multi-liter culture growth and harvest.
- Direct, hands-on experience operating ÄKTA FPLC systems, including independently designing, executing, and troubleshooting purification methods in UNICORN.
Preferred Qualifications:
- Experience with magnetic-bead–based purification platforms such as the Thermo KingFisher.
- Familiarity with cell-free or yeast expression systems.
- Hands-on experience programming and operating liquid handlers and robotic workstations.
The salary range for this role is $65,000 - $93,500. FL116 currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits.