Research Associate, Analytical Development

GenScript is seeking a Research Associate, Analytical Development to support analytical methods development, qualification, and execution for RNA, lipids, lipid nanoparticles (LNPs), and related bioconjugates at our Seattle site.

The successful candidate will perform hands-on laboratory work across HPLC/UHPLC, LC-MS, nano flow cytometry, and RNA/LNP analytical testing, supporting routine sample analysis, method development, optimization, troubleshooting, and method transfer in close collaboration with R&D, QC, Production, and other teams.

Key Responsibilities

• Chromatography and Analytical Testing: Prepare samples for testing, perform HPLC/UHPLC analyses, and support chromatographic methods for evaluating RNA and lipid attributes.
• LC-MS Characterization: Support LC-MS characterization of RNA, oligonucleotides, and related materials, and assist with spectral review and data processing.
• RNA and LNP Analytical Development: Perform analytical testing to support characterization of RNA, LNPs, and related bioconjugates.
• Nano Flow Cytometry and Targeted LNP Characterization: Prepare samples for flow-cytometry analysis and perform routine flow cytometer setup and sample acquisition.
• Laboratory Execution and Data Analysis: Perform routine wet-lab activities, process analytical results, and review data quality.
• Laboratory Operations and Cross-Functional Support: Support preparation of SOPs, instrument maintenance, and collaborate with scientists across teams.

Required Qualifications

• Bachelor's degree in Chemistry, Analytical Chemistry, Biochemistry, Biology, Biotechnology, Pharmaceutical Sciences, or a related scientific discipline.
• 0-5 years of relevant academic or industry laboratory experience.
• Hands-on experience with HPLC/UHPLC and/or LC-MS.
• Practical experience with flow cytometry.
• Strong fundamental wet-lab skills and attention to detail.

Preferred Qualifications

• Master's degree in Analytical Chemistry, Chemistry, Biochemistry, Pharmaceutical Sciences, or a related discipline.
• Previous experience working with mRNA, circRNA, oligonucleotides, lipids, LNPs, antibodies, or bioconjugates.
• Experience with analytical techniques such as HPLC-CAD, SEC, and RNA gel/capillary electrophoresis.

What Success Looks Like

The successful candidate will become a reliable contributor to GenScript's RNA and LNP analytical capabilities, generating high-quality data while developing independence in HPLC/UHPLC, LC-MS, flow cytometry, and RNA/LNP characterization.

Perks and Benefits

• Free colleague meals during shift
• Onsite gyms
• Medical, dental, and vision insurance
• 401(k) retirement plan with company match
• Paid parental leave and time off policy
• Flexible spending and health savings accounts
• Life and AD&D insurance, short- and long-term disability coverage, and more

Compensation

• Salary range: $65,000 – $80,000 total compensation, including bonus, depending on experience and qualifications.