Translational Scientist

We are seeking a Translational Scientist to join our team in Pennsylvania - Upper Providence, USA, Massachusetts - Cambridge, USA, or Stevenage. As a Translational Scientist, you will partner closely with biology, clinical development, translational medicine, biostatistics, DMPK, pathology, safety, and platform teams to deliver integrated development strategies.

You will translate complex preclinical and clinical datasets into actionable insights that inform target selection, patient stratification, and study design. You will drive efficient target progression and support clinical programs through integrated translational plans.

Key responsibilities include:

• Championing innovative approaches, technologies, and model systems that enhance portfolio differentiation and translational success
• Establishing and leading strategic collaborations with academic institutions, CROs, biotechnology companies, and key opinion leaders
• Building and maintaining a network of external experts to access emerging science, novel technologies, and unique research capabilities
• Contributing scientific leadership to evaluation and diligence activities for external opportunities
• Assessing target biology, translational evidence, competitive differentiation, and portfolio fit to support investment decisions
• Ensuring research activities are conducted in compliance with applicable policies, ethical standards, and quality expectations
• Helping optimize portfolio investments by prioritizing critical-path activities and recommending effective deployment of internal and external resources

Requirements:

• MD/PhD or PhD in cell or molecular biology, genetics, pharmacology, hepatology or a related discipline with extensive experience in preclinical biology and forward and reverse translation in liver disease
• Extensive experience in the pharmaceutical/biotechnology industry, with a focus on hepatology therapeutics (MASH and ALD) and a strong understanding of target mechanisms and translational evidence needed to support early clinical development
• Demonstrated ability to operate as a senior individual contributor and scientific thought leader, influencing decisions in a matrix environment through data-driven recommendations, clear communication, and strong collaboration
• Experience leading and managing external collaborations and diligence of business development opportunities
• Proven track record of advancing targets and/or assets through key discovery and early development milestones, including development of fit-for-purpose translational packages
• Strong knowledge of hepatology disease biology (MASH and ALD), pathways and mechanisms, and an appreciation of relevant co-morbidities

Preferred qualifications:

• Demonstrated strength as a translational scientist who can work with the Hepatology Disease Area Acceleration Team, the Hepatology Clinical Research Head, and aligned Early Development and Medicine Development Leaders
• Strong business acumen and understanding of commercial aspects, including marketing, sales, and market access
• Excellent communication and presentation skills, with the ability to effectively engage with internal and external stakeholders
• Demonstrated ability to work in a fast-paced, dynamic environment and manage multiple priorities
• Knowledge of regulatory requirements and compliance standards in the pharmaceutical industry

Benefits:

• Health care and other insurance benefits (for employee and family)
• Retirement benefits
• Paid holidays
• Vacation
• Paid caregiver/parental and medical leave

Salary range: $226,050 to $376,750 per year