Description
The Director, Real-World Evidence & Health Outcomes (RWE-HO), mRNA Vaccines will provide scientific and strategic leadership for the development and delivery of real-world evidence supporting GSK's mRNA vaccine portfolio, with a primary focus on influenza.
Responsibilities:
- Lead and contribute to the integrated RWE-HO strategy for mRNA influenza vaccines, aligned with clinical development, medical, regulatory and commercialization priorities.
- Translate strategic evidence gaps into clear research questions and fit-for-purpose study designs across pre-launch, launch and post-marketing phases.
- Provide expert scientific input to governance decisions, investment choices, evidence prioritization and risk mitigation.
- Lead the design, implementation and interpretation of post-marketing influenza vaccine effectiveness studies in the United States and other geographies.
- Ensure studies meet appropriate standards of scientific rigor, transparency, reproducibility and fitness for their intended decision-making purpose.
- Build productive collaborations with US academic investigators, healthcare systems, data partners and vaccine effectiveness research networks.
- Partner effectively with Clinical Development, Epidemiology, Medical Affairs, Regulatory, Safety, Biostatistics, Market Access, Data Science and Commercial teams.
- Lead multiple complex projects, budgets and external research collaborations, ensuring quality, timely delivery and appropriate escalation of risks.
- Influence senior stakeholders without direct authority and communicate complex epidemiological concepts in a clear, decision-focused manner.
- Mentor colleagues and contribute to strengthening RWE-HO capabilities, standards and innovation across the organization.
Basic Qualifications:
- PhD, ScD, DrPH, MD, PharmD, MPH or equivalent advanced degree in epidemiology, public health, pharmacoepidemiology, health outcomes research or a related quantitative discipline.
- 5+ years experience in real-world evidence, epidemiology or health outcomes research within the pharmaceutical or vaccine industry, academia, public health or a comparable environment.
- Experience designing, conducting and interpreting post-marketing vaccine studies in the United States.
- Research experience with vaccine effectiveness studies.
- Experience using large US healthcare databases, including administrative claims, electronic health records or linked real-world datasets.
- Experience leading complex studies from concept through delivery, interpretation and scientific dissemination.
- Demonstrated effectiveness in global, cross-functional matrix teams and in managing internal and external stakeholders.
Preferred Qualifications:
- Direct experience with influenza vaccine effectiveness studies in the United States.
- Experience with US Medicare, commercial claims, EHR and linked claims/EHR data.
- Knowledge of US influenza vaccination recommendations, vaccine delivery and healthcare systems.
- Experience studying severe influenza, hospitalization, cardiovascular complications or other downstream outcomes.
- Experience leading global evidence-generation plans or multi-country observational studies.
What success looks like: The successful candidate will combine deep technical expertise with strategic asset-level thinking. They will design credible US post-marketing studies, anticipate the methodological challenges specific to influenza, and convert complex evidence needs into practical solutions. They will be a trusted scientific partner who can influence decisions, build external credibility and deliver evidence that supports the value and appropriate use of GSK's mRNA vaccines.