Senior Software Engineer, Site Reliability

As a Senior Software Engineer, Site Reliability at Freenome, you will be a founding member of the Site Reliability Engineering (SRE) team, helping to define the culture and build systems that keep their regulated, cloud-based production environments reliable as they transition from research to commercial operations.

You will help design, implement, and operate observability, reliability, and incident management systems and practices across their clinical lab systems and regulated commercial workloads. This will involve partnering with engineering teams to define service-level indicators (SLIs), objectives (SLOs), and error budgets; building runbooks and operational playbooks; and developing the monitoring and automation needed to ensure that their systems are reliable and compliant.

Key responsibilities:

• Define and implement observability practices (metrics, traces, dashboards, logs, alerts) for production systems.
• Partner with product, engineering, and lab teams to develop and maintain incident response playbooks and escalation procedures.
• Partner with engineering teams to define SLIs/SLOs and establish error budgets.
• Participate in on-call rotation for production systems, focusing on automation and self-healing.
• Contribute to production deployment and change-management processes that meet FDA and compliance requirements.
• Automate operational tasks, reducing manual intervention.
• Contribute to production systems and designs with the goal of improving reliability.
• Use Infrastructure as Code (IaC) to manage and deploy team-owned infrastructure and subsystems.
• Help build out the SRE practice.
• Work closely with engineering, product, and lab teams to understand service reliability needs.
• Partner with TPMs, RA/QA, and compliance stakeholders to align operational practices with regulatory requirements.
• Participate in cross-functional incident reviews and postmortems.
• Share knowledge and document operational standards for consistency and onboarding.
• Design and run fire drills/tabletop exercises and disaster recovery exercises.
• Independently drive reliability improvements in scoped systems or services.
• Provide mentorship to peers on observability, incident management, and operational best practices.
• Help build and evolve Freenome's reliability practices and contribute to team strategy discussions.

Requirements:

• Bachelor's degree in Computer Science, Engineering, or equivalent experience.
• 5+ years in software engineering or Infra/DevOps/SRE roles (Python or Go preferred).
• Experience deploying cloud infrastructure via automation (e.g., Terraform, Pulumi, Bicep/ARM).
• Hands-on experience operating production workloads in cloud environments.
• Familiarity with Kubernetes (AKS, GKE, or EKS).
• Strong troubleshooting and root-cause analysis skills in distributed systems.
• Experience with observability platforms (e.g., DataDog, Prometheus/Grafana, OpenTelemetry).
• Ability to define and implement metrics, dashboards, and alerting.
• Demonstrated ability to work autonomously and own technical outcomes.
• Strong understanding of cloud Infrastructure and Networking architectures and automation.

Nice to haves:

• Experience supporting regulated environments (healthcare, biotech, financial).
• Familiarity with compliance-driven change management and release processes (FDA, HIPAA).
• Experience with incident management platforms (e.g., Incident.io, ServiceNow, Opsgenie, Pagerduty).
• Knowledge of CI/CD deployment strategies and change automation.
• Experience with both GCP and Azure cloud platforms.
• Interest in mentorship and system reliability practices at scale.

Benefits:

• The US target range of base salary rate for new hires is $131,325 - $189,525.
• Eligibility to receive equity, cash bonuses, and a full range of medical, financial, and other benefits.