Skip to content
Updated How AI-exposed are the skills employers are hiring for? See the data →

From the employer's careers site First seen 8 Nov 2026

Senior Principal Engineer

The employer hasn't listed a salary.

Apply on GlaxoSmithKline (GSK)

Description

We are seeking a highly skilled Senior Principal Engineer specializing in Cloud Integrations and Enterprise Platforms to drive technical excellence, innovation, and seamless integration across our enterprise ecosystem.

Key Responsibilities:

1. Cloud Integration & Enterprise Platforms

  • Design and implement modern cloud-native architectures leveraging Azure Data Lake, Azure Cloud, Databricks, Unity Catalog, and Delta Share.
  • Optimize enterprise-wide integration services using Azure Service Bus, API Management, Event Grid, and Logic Apps.
  • Ensure seamless data integration across Salesforce (Health Cloud, Service Cloud, Marketing Cloud), Azure, and third-party applications through REST/SOAP APIs and middleware platforms like MuleSoft.
  • Lead secured collaborative development environments for cross-functional teams.

2. Application Ownership & Technical Excellence

  • Own the end-to-end design, development, and maintenance of AI/GenAI, data, and integration platforms.
  • Serve as a technical design authority, ensuring best practices in cloud scalability, security, and AI governance.
  • Implement and enforce ITMS (IT Management System) controls, ensuring compliance and operational excellence.

3. Delivery Oversight & Vendor Management

  • Oversee end-to-end project execution, working with internal teams and external vendors to deliver high-quality solutions.
  • Manage vendor-led scrum teams and enforce best practices in software development, coding standards, and security policies.
  • Define and drive the adoption of FinOps, CloudOps, and Governance models for AI and cloud-based platforms.

4. Innovation & Continuous Improvement

  • Drive next-generation innovation projects, including GenAI, Conversational AI, and AI-driven automation.
  • Optimize pharmaceutical research and commercial data workflows using cutting-edge AI and data engineering tools.
  • Foster a culture of continuous learning and technical mentorship within the engineering team.

Required Skills & Qualifications:

  • 15+ years of professional experience with a qualification Bachelor's/Master's degree in a relevant field.
  • Strong hands-on experience with Azure services, including Azure Cloud, Azure Data Lake, Service Bus, Event Grid, API Management, and Databricks.
  • Expertise in Salesforce (Health Cloud, Service Cloud, Marketing Cloud) and CRM integrations.
  • Experience in designing scalable APIs, cloud-based microservices, and integration platforms.
  • Strong knowledge of security, ITMS controls, and compliance frameworks (GxP, FDA, EMA).
  • Excellent leadership, stakeholder management, and vendor governance skills.

For more fresh new jobs, check out yubhub.co.

Skills

Required

  • Azure services
  • Salesforce
  • CRM integrations
  • API design
  • Cloud-based microservices
  • Integration platforms
  • Security
  • ITMS controls
  • Compliance frameworks

Nice to have

  • Azure Certifications
  • Salesforce Certifications
  • Experience in Pharma, Healthcare, or Life Sciences industries
Apply on GlaxoSmithKline (GSK)