Analytical Scientist

Join GSK's Extended Characterization Europe team as an Analytical Scientist, supporting the analytical development and characterisation of biopharmaceutical molecules.

This predominantly laboratory-based role will use LC-MS and LC-MS/MS to generate scientific understanding that supports the development and control of new drug substances and products.

You will work independently and collaboratively across Discovery and CMC Development teams, combining strong scientific judgement, data analysis, communication and organisation to help deliver a novel pipeline of medicines to patients.

In this role you will

• Plan, execute and interpret LC-MS and LC-MS/MS experiments for the characterisation of biopharmaceutical molecules.
• Develop, optimise and troubleshoot analytical methods, experiments and instrumentation.
• Investigate molecular structure, product quality attributes and post-translational modifications to support the identification and assessment of critical quality attributes.
• Support early-phase programmes through forced degradation studies, comparability assessments, process understanding and technical transfer.
• Critically evaluate complex analytical datasets, draw scientifically robust conclusions and recommend appropriate next steps.
• Communicate findings clearly, prepare high-quality technical documentation and maintain high standards of data integrity, quality and laboratory safety.

Basic Qualifications & Skills:

• PhD, MSc or equivalent relevant experience in Analytical Chemistry, Chemistry, Biochemistry, Pharmaceutical Sciences or a related discipline.
• Experience of LC-MS or LC-MS/MS method development and execution for biopharmaceuticals in a pharmaceutical or biotechnology setting.
• Good understanding of protein biochemistry, post-translational modifications and the relationship between molecular structure, function and product quality attributes.
• Ability to independently plan and execute analytical experiments and troubleshoot scientific and technical challenges.
• Experience working in matrix teams and delivering time-bound, multi-project work packages with strong organisation and prioritisation.
• Strong data interpretation, written and verbal communication skills, with a commitment to data integrity, scientific standards, safe laboratory practice and effective documentation.

Preferred Qualifications & Skills:

• Knowledge of protein glycosylation and analytical workflows for N-linked glycan analysis.
• Understanding of antibody sequence and structure-function relationships and critical quality attributes.
• Experience with liquid-handling automation systems.
• Experience with mass spectrometry data-analysis software such as Protein Metrics or equivalent platforms.
• Experience handling large datasets and conducting statistical analysis using software such as JMP or SIMCA.
• Understanding of biopharmaceutical manufacturing processes and confidence working across teams with shared laboratory instrumentation.

Benefits

• Competitive salary
• Annual bonus based on company performance
• Healthcare and wellbeing programmes
• Pension plan membership
• Shares and savings programme
• Hybrid working model