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senior full-time $160,000 to $237,500 Palo Alto, CA

First indexed 24 Oct 2026

Description

The Chief of Staff serves as a scientific and strategic partner, proxy, and "shared brain" to the Institute's Executive Director and Core Investigator.

This is a technical, full-time role for someone who can engage substantively with the science, from CRISPR-based transcriptome engineering and functional genomics to computational modeling and disease biology, and translate that engagement into sharp decision-making, program execution, and cross-disciplinary coordination.

Responsibilities:

  • Serve as a scientific and strategic daily thought partner to the Executive Director, engaging critically with scientific work across the lab, institute and external partnerships
  • Own the operating rhythm of the Executive Director’s office, including a complex, shifting schedule and the prioritization of conflicting technical and organizational demands
  • Gather and synthesize technical information and open decisions from across the Institute into clearly framed options, trade-offs, and recommendations
  • Design strategic and effective meeting and offsite pre-reads, meeting agendas and meeting followup for Arc’s leadership team as well as scientific teams
  • Drive high-priority scientific programs, collaborations and special projects from inception through execution
  • Partner with the Executive Director and leadership team on defining annual and longer term strategic goals for the institute
  • Unblock science by organizing and stewarding scientific collaborations, within the Institute and with external partners
  • Translate complex technical work for varied audiences
  • Handle confidential scientific and organizational information with care, thoughtfulness, and discretion at all times

Requirements:

  • A Ph.D. (or equivalent research training) with a demonstrated scientific track record, or comparable technical depth from a consulting or founder path, plus 5-12+ years of experience
  • Background in one or more relevant biology areas (e.g., genome or transcriptome engineering, functional genomics, neuroscience, molecular/cell biology, multi-omics, or computational biology)
  • Demonstrated strength in technical information gathering, stakeholder and dependency mapping and management, and synthesizing complex scientific information into clear options and actionable recommendations for decision makers
  • Track record of managing complex, cross-functional projects in a research environment from inception through execution
  • Evidence of translating technical or scientific work for non-specialist audiences
  • Excellent written and verbal communication skills
  • Solution-oriented and adept at navigating shifting priorities and rapid change; unflappable, proactive, and discreet

Preferred Qualifications:

  • Ph.D. in the life sciences or a closely related field
  • Hands-on experience with CRISPR/gene- or RNA-editing technologies, functional genomic screens, or high-throughput experimental platforms
  • Experience with computational biology, machine learning, or large-scale genomic data
  • Experience organizing scientific collaborations or programs, within an institution and with external partners
  • Experience supporting board preparation, scientific offsites, and executive or scientific communications

Benefits:

  • The base salary range for this position is $160,000 to $237,500
  • Eligible to receive an annual discretionary bonus
  • Eligible to participate in the Institute’s Compound Cash Grant Program (CCGP)
This listing is enriched and indexed by YubHub. To apply, use the employer's original posting: https://job-boards.greenhouse.io/arcinstitute/jobs/6129232004