Description
Quotient Therapeutics is seeking a Director or Senior Director of Antibody Discovery to define and lead the company's antibody discovery strategy. You will drive the delivery of therapeutic antibody projects and build the company's antibody drug discovery platform using cutting-edge technologies.
Key responsibilities include:
- Providing expert advice on the feasibility of antibody tractable targets and the conception of high-value drug molecules
- Presenting antibody discovery strategies to internal R&D committees
- Driving decision making on construct design, format, and developability for new antibody programs
- Independently carrying out lead sequence and format optimizations using rational, structure-based, and in silico/AI/ML design approaches
- Leading cross-functional teams to execute drug discovery programs through lead generation, development candidate nomination, and IND submission
- Identifying, selecting, and managing external CROs/vendors, consultants, and academic collaborators
- Building and maintaining networks of external experts to pressure-test hypotheses and refine strategies
Requirements:
- Proven experience advancing protein therapeutics through drug discovery phases to development
- Expertise in structure-based protein engineering and design of antibodies
- Skilled in antibody engineering, including use of in silico, structure-based, and AI/ML approaches
- Project leadership experience in pharmaceutical industry R&D environment
- Track record of advocating for acquisition or creation of new technologies for accelerated antibody design
The salary range for this role is $179,000 - $236,500. Quotient Therapeutics offers healthcare coverage, annual incentive program, retirement benefits, and a broad range of other benefits.