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OpenAI

Software Engineer, Life Sciences

OpenAI
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hybrid senior Full time $347K - $450K San Francisco

First indexed 7 Oct 2026

Description

We are seeking an experienced full-stack product engineer with strong backend skills to join our growing Life Sciences team.

The OpenAI Life Sciences team works at the intersection of advancing frontier life sciences model capabilities and building products to help scientists accelerate their research and leverage the full potential of AI for scientific work.

As a Software Engineer, Life Sciences, you will:

  • Design backend services, APIs, and integrations that connect users with models, scientific tools, and laboratory services.
  • Create intuitive interfaces that help scientists navigate complex workflows.
  • Own projects from problem definition and technical design through launch, operation, and iteration.
  • Work with scientific and research partners to identify user needs and prioritize valuable product improvements.
  • Partner with dedicated infrastructure engineers on performance, reliability, and scaling.
  • Make thoughtful engineering decisions that balance speed, quality, and long-term maintainability.

You might thrive in this role if you:

  • Have strong software engineering fundamentals and depth in backend development, alongside the ability to build across the stack.
  • Have shipped and operated products used by large user bases.
  • Bring strong product sense and can translate ambiguous needs into useful software.
  • Work autonomously, make sound technical decisions, and drive projects forward with limited direction.
  • Enjoy hands-on building and taking ownership within a lean team.
  • Are excited about advances in AI and how they could change scientific work.
  • Learn unfamiliar domains quickly and collaborate effectively with scientific and technical partners.

Compensation

  • $347K – $450K • Offers Equity

The base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. If the role is non-exempt, overtime pay will be provided consistent with applicable laws. In addition to the salary range listed above, total compensation also includes generous equity, performance-related bonus(es) for eligible employees, and the following benefits.

Benefits

  • Medical, dental, and vision insurance for you and your family, with employer contributions to Health Savings Accounts
  • Pre-tax accounts for Health FSA, Dependent Care FSA, and commuter expenses (parking and transit)
  • 401(k) retirement plan with employer match
  • Paid parental leave (up to 24 weeks for birth parents and 20 weeks for non-birthing parents), plus paid medical and caregiver leave (up to 8 weeks)
  • Paid time off: flexible PTO for exempt employees and up to 15 days annually for non-exempt employees
  • 13+ paid company holidays, and multiple paid coordinated company office closures throughout the year for focus and recharge, plus paid sick or safe time (1 hour per 30 hours worked, or more, as required by applicable state or local law)
  • Mental health and wellness support
  • Employer-paid basic life and disability coverage
  • Annual learning and development stipend to fuel your professional growth
  • Daily meals in our offices, and meal delivery credits as eligible
  • Relocation support for eligible employees
  • Additional taxable fringe benefits, such as charitable donation matching and wellness stipends, may also be provided.
This listing is enriched and indexed by YubHub. To apply, use the employer's original posting: https://jobs.ashbyhq.com/openai/4f0d64b8-bfa7-4c30-9972-a10d74b49075