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From the employer's careers site First seen 27 Oct 2026

(Senior) Scientist, Optical Technologies

Salary

$100,000 - $180,000 per year

Apply on Flagship Pioneering

Description

Help Expand What We Can See in Biology

At Flagship Pioneering, we build companies around bold scientific ideas. Flagship Labs is our innovation foundry where teams originate, test, and scale breakthrough technologies that can become new bioplatforms.

We are looking for a scientist with deep hands-on experience in optics and vibrational spectroscopy to join the team and help turn promising experimental opportunities into practical capabilities for the platform. This is a zero-to-one role for an engineering-minded scientist who enjoys turning new ideas into practical experiments.

Responsibilities:

  • Design and execute experiments using advanced optical and vibrational spectroscopy measurement techniques to characterize biological systems.
  • Own a portfolio of internal and external experiments, coordinating work across CROs, university core facilities, academic collaborators, and internal teams.
  • Develop, refine, and document experimental workflows, protocols, and SOPs to improve measurement quality, reproducibility, and operational efficiency.
  • Troubleshoot instrumentation, identify sources of experimental variability, and improve data quality and reproducibility.
  • Stay current across relevant fields to identify promising new experiments and applications.
  • Contribute to the scientific strategy and technical roadmap of a founding-stage venture.

Qualifications Required:

  • PhD (or equivalent experience) in physics, biophysics, chemistry, engineering, bioengineering, or a related discipline.
  • Deep hands-on experience developing and applying optical microscopy and vibrational spectroscopy techniques such as Raman microscopy, IR spectroscopy, or related methods.
  • Strong experimental background and demonstrated ability to independently execute and troubleshoot complex experiments.
  • Solid understanding of the physics and engineering of optical instrumentation.
  • Strong scientific judgment and the ability to distinguish meaningful biological signals from technical artifacts.

Preferred:

  • Experience developing or optimizing advanced Raman spectroscopy (e.g. CARS, SRS) or IR spectroscopy (e.g. photothermal IR), or related techniques.
  • Experience working with biological samples such as cells or tissue.
  • Familiarity with cell culture or live cell assays is a plus.
  • Familiarity with molecular or cell biology sufficient to understand literature and adopt new experimental protocols.
  • Programming or scripting experience (Python, MATLAB, or similar) for instrument automation and experimental data analysis.
  • Experience working with external collaborators, university core facilities, or CROs.
  • Previous experience in startup, translational, or highly interdisciplinary research environments.

Why Join FL120? This is an opportunity to join a founding scientific team exploring an entirely new experimental platform. Success will require curiosity, creativity, and a willingness to cross traditional disciplinary boundaries.

FL120 currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits.

Skills

Required

  • optics
  • vibrational spectroscopy
  • Raman microscopy
  • IR spectroscopy
  • physics
  • biophysics
  • chemistry
  • engineering
  • bioengineering

Nice to have

  • CARS
  • SRS
  • photothermal IR
  • Python
  • MATLAB
  • cell culture
  • live cell assays
  • molecular biology
  • cell biology

Ready to apply?

You apply with the employer directly. Their original posting is here: https://job-boards.greenhouse.io/flagshippioneeringinc/jobs/8695960002

Apply on Flagship Pioneering