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From the employer's careers site First seen 3 Nov 2026

Principal Site Activation Manager

Syneos Health Morrisville, NC Hybrid senior full-time

Salary

$97,300 - $170,300 per year

Apply on Syneos Health

Description

We are seeking a Principal Site Activation Manager to lead and oversee global site activation activities from study start-up through site readiness. You will develop and execute country and site activation strategies, manage timelines, risks, and deliverables across multiple studies or programs, and partner closely with Clinical Operations, Regulatory Affairs, Contracts & Budgets, and external stakeholders.

Responsibilities:

  • Lead and oversee global site activation activities from study start-up through site readiness
  • Develop and execute country and site activation strategies
  • Manage timelines, risks, and deliverables across multiple studies or programs
  • Partner closely with Clinical Operations, Regulatory Affairs, Contracts & Budgets, and external stakeholders
  • Drive performance metrics and ensure activation milestones are achieved
  • Provide guidance and oversight to Site Activation Managers and study teams
  • Support issue escalation and resolution for complex start-up challenges
  • Ensure compliance with regulatory requirements, SOPs, and sponsor expectations

Benefits:

  • Company car or car allowance
  • Health benefits, including Medical, Dental, and Vision
  • Company match 401k
  • Eligibility to participate in Employee Stock Purchase Plan
  • Eligibility to earn commissions/bonus based on company and individual performance
  • Flexible paid time off (PTO) and sick time

Skills

Required

  • Clinical Operations
  • Regulatory Affairs
  • Contracts & Budgets
  • Site Activation
Apply on Syneos Health