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From the employer's careers site First seen 27 Oct 2026

Senior / Principal Computational Biologist

Cellarity Somerville, MA senior full-time

Salary

$179,000 - $236,000 per year

Apply on Cellarity

Description

Join Cellarity, a rapidly growing biotech company, as a Senior / Principal Computational Biologist. You will play a critical role in bringing new medicines to patients by applying your skills to real-world therapeutic challenges. As a computational biology lead, you will collaborate with cross-functional teams to co-develop hypotheses from cell atlases and advance programs from biological model development through hit identification and lead optimization.

Responsibilities:

  • Act as the CompBio lead and core team representative on cross-functional drug programs
  • Develop and lead data analysis strategies and ideation across diverse projects
  • Apply computational biology and machine learning tools to generate insights and hypotheses from high-dimensional molecular datasets
  • Use transcriptomic data to develop disease hypotheses, evaluate models, analyze perturbation effects, and validate hits and leads
  • Work with experimental scientists to ensure study designs and data deliver high-value readouts and actionable insights
  • Contribute to internal AI agent development for Cellarity's scientific use cases

Requirements:

  • Ph.D. or equivalent in biology, computational biology, or related scientific field
  • 3+ years of relevant industry experience
  • Extensive experience in analyzing and deriving hypotheses from single-cell and bulk transcriptomic data
  • Demonstrated understanding of molecular and systems biology, diverse molecular data types, and analysis tools
  • Practical programming and scripting skills, preferably in Python
  • Fluency with AI tools to accelerate daily scientific work

Nice to Have:

  • Background in metabolic or liver diseases, autoimmune disease, or hematology
  • Experience with generating, analyzing, and deriving hypotheses from other single-cell omics data types or large-scale clinical datasets
  • Experience driving an impactful and relevant project within industry
  • Background in statistics or machine learning

Benefits:

  • Healthcare coverage
  • Annual incentive program
  • Retirement benefits
  • Broad range of other benefits

Skills

Required

Nice to have

  • metabolic diseases
  • liver diseases
  • autoimmune disease
  • hematology
  • statistics
  • clinical data analysis

Ready to apply?

You apply with the employer directly. Their original posting is here: https://job-boards.greenhouse.io/flagshippioneeringinc/jobs/8742220002

Apply on Cellarity