Description
Syneos Health is seeking an experienced Clinical Project Manager II to join a high-performing sponsor-dedicated team supporting a diverse portfolio of oncology studies.
As a Clinical Project Manager II, you will help drive the operational execution and delivery of global oncology clinical trials, ensuring studies are conducted efficiently, compliantly, and according to established timelines.
Key Responsibilities:
- Support and partner with Clinical Study Leads and cross-functional study teams on global oncology trials
- Lead day-to-day study management activities across study startup, conduct, maintenance, and closeout
- Manage study timelines, deliverables, risks, and issue resolution
- Oversee external vendors, CROs, central laboratories, imaging vendors, and specialty providers
- Coordinate Clinical Trial Team (CTT) meetings and drive action item follow-up
- Support study-level planning, forecasting, and operational strategy execution
- Monitor study performance metrics and proactively identify areas requiring intervention
- Ensure inspection readiness and compliance with applicable regulations and sponsor requirements
- Collaborate with stakeholders across Clinical Operations, Data Management, Biostatistics, Medical Monitoring, Regulatory Affairs, Safety, Supply Chain, and Quality
- Contribute to study status reporting and executive-level communications
- Support achievement of study milestones, enrollment targets, database locks, and study closeout activities
Required Qualifications:
- Bachelor's degree in a scientific, healthcare, or related field
- 3+ years of Clinical Project Management experience supporting global oncology clinical trials
- Experience managing studies across multiple countries and regions
- Vendor management experience required
- Strong understanding of clinical trial operations and study lifecycle management
- Experience supporting Phase I, Phase II, Phase III, and/or Phase IV oncology studies
- Strong working knowledge of ICH-GCP guidelines and clinical research regulations
- Proficiency with Microsoft Office Suite
- Ability to work effectively within global, cross-functional matrix organizations
Oncology Therapeutic Area Experience:
- Direct clinical trial experience supporting one or more oncology indications, such as lung cancer, melanoma, renal cell carcinoma, bladder cancer, head & neck squamous cell carcinoma, triple-negative breast cancer, cervical cancer, gastric and gastroesophageal cancers, esophageal cancer, hepatocellular carcinoma (liver), endometrial cancer, ovarian cancer, colorectal cancer, biliary tract cancer, prostate cancer, urothelial carcinoma, hematologic malignancies (multiple myeloma, lymphoma, leukemia), antibody-drug conjugates (ADCs), personalized cancer vaccines, KRAS inhibitors, T-cell engagers, cell-directed immunotherapies
Preferred Qualifications:
- Experience independently leading global oncology studies
- Experience supporting complex, multi-regional Phase II and Phase III programs
- Experience with early-phase oncology studies (Phase I/Ib)
- Experience with immuno-oncology, targeted therapies, cell therapy, or hematologic malignancies
- Familiarity with CTMS, eTMF, IRT/RTSM, and clinical data review platforms
- Experience working in sponsor-dedicated or FSP environments
Benefits:
- Salary Range: $120,000-135,000
- Company car or car allowance
- Health benefits to include Medical, Dental and Vision
- Company match 401k
- Eligibility to participate in Employee Stock Purchase Plan
- Eligibility to earn commissions/bonus based on company and individual performance
- Flexible paid time off (PTO) and sick time