Description
GSK is seeking an Oncology Safety Lead to provide medical and scientific leadership in the safety evaluation and risk management of GSK's oncology assets in clinical development.
The successful candidate will be responsible for interpreting safety data, identifying and escalating safety signals, and delivering clear, evidence-based recommendations to support benefit-risk decisions.
Key responsibilities include:
- Leading pharmacovigilance and risk management activities for assigned oncology assets and clinical trials
- Defining and driving strategy for the evaluation and management of safety issues across the clinical development lifecycle
- Analysing and interpreting clinical data, literature, and emerging evidence to identify and assess safety signals
- Providing expert medical input into the safety components of global regulatory submissions
- Applying sound clinical judgement to complex and sometimes conflicting data sets to inform benefit-risk decisions
- Ensuring timely escalation of safety concerns in line with governance processes
- Representing Safety on cross-functional Clinical Matrix and Project Teams
- Leading cross-functional teams to address urgent and complex product safety issues
- Building strong, collaborative relationships across functions and geographies
- Coaching and mentoring colleagues, contributing to capability development within the organisation
The ideal candidate will have:
- A medical degree with current GMC registration (or eligibility to practise in the UK) and relevant clinical experience
- Completion of formal postgraduate clinical training (e.g., residency or specialty training)
- Significant experience in pharmacovigilance, drug safety, or medical affairs
- Demonstrated expertise in signal detection, evaluation, and risk management
- Strong understanding of clinical development and post-marketing safety processes
- Experience working effectively in matrixed, cross-functional environments
- Excellent written and verbal communication skills, including preparation of medical and regulatory documents
- Strong clinical judgement and the ability to deliver clear, evidence-based recommendations
This is a hybrid role based in the United Kingdom, with remote working supported to balance focused work and stakeholder engagement.