Description
We are seeking a biostatistician with strong experience in real-world data (RWD) with observational study design and safety study experience in addition to RWE Safety experience.
Job Responsibilities
- Design and execute real-world evidence (RWE) studies using EMR and claims data; Conducting data specs, SAP and protocol with key research objectives
- Develop and apply robust statistical methodologies, including:
- Causal inference methods (e.g., propensity score methods, weighting, matching; GLM or GLMM, MMRM; survival analysis; random forest)
- Trial emulation frameworks
- External control arm development and borrowing strategies
- Perform data analysis using healthcare coding systems (e.g., ICD, NDC)
- Conduct sample size estimation and power calculations for observational and hybrid study designs
- Collaborate cross-functionally with stakeholders across:
- HEOR
- Market Access
- Regulatory
- Clinical Development
- Translate complex analytical results into clear, actionable insights, e.g. powerpoint or study report for decision-making
- Support methodological innovation in RWE, including integration of machine learning approaches where appropriate
Required Qualifications
- M.S. or Ph.D. in Biostatistics, Statistics, Epidemiology, or related field
- ≥5 years of experience in RWD/RWE analytics (industry or equivalent)
- Strong experience with EMR and/or claims data
- Proficiency in healthcare coding systems (e.g., ICD, NDC)
- Programming expertise in at least one of: SAS, R, or Python
- Working knowledge with SQL logic and OMOP data structures
- Solid understanding of:
- Causal inference methods
- Observational study design
- Sample size and power considerations
Preferred Qualifications
- Ph.D. strongly preferred
- Familiarity with:
- Trial emulation methodologies
- External control borrowing / hybrid designs
- Basic machine learning methods applied to RWD
- Demonstrated ability to work across multiple therapeutic areas (TAs) in a fast-paced environment
- Strong communication and stakeholder engagement skills
Benefits
- Company car or car allowance
- Health benefits to include Medical, Dental and Vision
- Company match 401k
- Eligibility to participate in Employee Stock Purchase Plan
- Eligibility to earn commissions/bonus based on company and individual performance
- Flexible paid time off (PTO) and sick time