Research Associate II, Production

BigHat Biosciences is seeking a self-motivated individual for a Research Associate II, Production role to power its high-throughput, automated platform for antibody production and deep molecular characterization.

Key Responsibilities

• Perform automated and manual high-throughput processing on the BigHat platform, including DNA preparation, protein expression, and protein characterization.
• Contribute to scaling up BigHat's platform and production-grade data generation.
• Support BigHat's Platform Reagents & Assay Support (PRAS) function by contributing to in-house reagent manufacturing efforts.
• Execute experiments to optimize the performance efficiency of BigHat's platform.
• Keep detailed records of all experiments using BigHat's documentation tools and clearly communicate results and challenges.
• Collaborate on creating laboratory standard operating procedures (SOPs) for sample processing.
• Collaborate closely with BigHat team members to identify, design, and implement critical process and operational improvements to production workflows and laboratory systems.
• Operate automated liquid handlers and analytical instruments to ensure all lab and platform operations run efficiently.

Skills, Knowledge & Expertise

• BS in Biology or Chemistry, with 2+ years of industry experience.
• Experience in process execution, laboratory method development, optimization, and troubleshooting.
• Ability and willingness to work specific workday schedules as needed.
• Hands-on experience with automated liquid handlers (e.g., Hamilton, OpenTrons, Tecan, Agilent systems) and LIMS.
• Experience with molecular biology techniques and general lab practices.
• Efficient time management and ability to work on several projects simultaneously in a dynamic start-up environment.
• Strong interpersonal skills and ability to effectively communicate with members of a multidisciplinary team.
• Excellent record-keeping abilities to document experimental work and analytical data.

Benefits

The salary estimated for this position is $88,000 - $100,000 + bonus + options + benefits. Compensation will vary depending on job-related knowledge, skills, and experience.