Description
Quotient is seeking an experienced Scientific Manager to lead the day-to-day execution and delivery of its High Throughput Laboratory.
The Scientific Manager will report to the Head of High Throughput Laboratory and be responsible for coordinating laboratory activities across Histology, Flow Cytometry, Molecular Biology, and Sample Management.
Key Responsibilities:
- Laboratory Delivery: Coordinate day-to-day laboratory execution across multiple disease programmes, ensuring samples progress efficiently through laboratory workflows.
- Translate project priorities into detailed laboratory work plans and schedules, ensuring resources, equipment, and personnel are effectively allocated.
- Partner with Disease Project teams, the Head of High Throughput Laboratory, and Research Project Management to prioritise work, manage competing demands, and resolve operational bottlenecks.
- Monitor laboratory throughput, turnaround times, sample progression, and resource utilisation, proactively identifying risks to delivery and implementing corrective actions.
- Maintain clear visibility of sample status throughout the laboratory workflow, ensuring timely communication of progress, risks, and delays to project teams.
- People Leadership: Line manage and develop direct reports through coaching, regular feedback, and performance management.
- Promote a culture of accountability, collaboration, and continuous learning within the laboratory team.
- Support recruitment, onboarding, training, and competency assessment of laboratory staff.
- Ensure appropriate laboratory cover and resource planning to support changing portfolio demands.
- Scientific Delivery: Remain scientifically hands-on where required, supporting laboratory activities and troubleshooting technical issues to maintain programme delivery.
- Provide technical oversight across Histology, Flow Cytometry, and Molecular Biology workflows, ensuring high standards of scientific quality and reproducibility.
- Support implementation and operational adoption of new laboratory processes, technologies, and workflow improvements in partnership with Assay Development and Automation.
- Work closely with scientific leaders to understand future project requirements and ensure laboratory readiness to support programme delivery.
Laboratory workflows supported by the team include:
- Histology: Tissue fixation, embedding, sectioning, histochemistry (H&E, IHC), and slide preparation.
- Flow Cytometry: Tissue dissociation, FACS/FANS, cell and nuclei counting, immunostaining, and sample preparation.
- Molecular Biology: DNA/RNA extraction, nucleic acid quality assessment, library preparation, and sequencing submissions.
Qualifications:
- Bachelor's degree with significant relevant industry experience (typically 6+ years).
- Experience working within high-throughput laboratory environments and/or rapidly scaling biotechnology organisations.
- Demonstrated experience coordinating laboratory workflows across multiple concurrent scientific projects.
- Experience line managing or mentoring laboratory users.
- Hands-on expertise in a range of skills across Histology, Flow Cytometry, and/or Molecular Biology.
- Familiarity with ELN and/or LIMS systems for laboratory documentation and sample tracking.
Values and Behaviours:
- Encourage respectful disagreement and cultivate open-minded, ego-free interactions that continuously improve scientific thinking and execution.
- Seek diverse perspectives, practice active listening, and ensure every contribution is valued.
- Recognise the impact of your behaviour, communication, and leadership style, fostering trust, accountability, and collaboration.