# Principal Software Engineer - Agentic Platform

**Company**: Flagship Pioneering
**Location**: Cambridge, MA
**Experience**: senior
**Job type**: full-time
**Salary**: $188,000 - $257,500
**Category**: Engineering
**Industry**: Technology

**Apply**: https://job-boards.greenhouse.io/flagshippioneeringinc/jobs/8584555002?utm_source=yubhub.co&utm_medium=jobs_feed&utm_campaign=apply
**Canonical**: https://yubhub.co/jobs/job_d0844438-fb1

## Description

We are seeking a Principal Software Engineer to own the underlying agentic platform: the durable orchestration layer on which long-running, multi-agent, multi-model scientific workflows run reliably.

Key Responsibilities:

- Own the agentic platform end to end, from research prototype to production, building the durable orchestration layer for long-running, multi-stage scientific workflows.

- Architect workflow orchestration, evaluation frameworks, and event-driven distributed systems that deliver scale, resilience, and reliability.

- Define SDK abstractions and API contracts between model and agent outputs and downstream consumers, decoupling rapid model iteration from product stability and reducing integration friction across teams.

- Deliver infrastructure-as-code reference implementations (AWS CDK, Terraform, containerized services) and transform exploratory AI proof-of-concepts into hardened, reusable patterns adopted across product domains.

- Own platform cost-efficiency and scalability while preserving the performance and accuracy that our experiments and end users require.

- Explore and template agent design and deployment patterns, and set technical standards, code quality, and architectural direction for the platform.

- Partner across teams (modeling and agent teams, product) to align on integration points, dependency timelines, and delivery, and mentor engineers and scientists.

Professional Experience & Qualifications:

- B.S. or M.S. in Computer Science, Engineering, or a related field, with 10+ years of professional software development experience.

- Demonstrated track record architecting and maintaining large-scale distributed systems in production at technology companies.

- Deep expertise in workflow orchestration and event-driven architecture, including stateful execution, idempotency, durable retries, and replay.

- Strong cloud-native engineering on AWS with infrastructure-as-code, containerization, and autoscaling.

- Proven ability to take systems from prototype to hardened, observable, operationally excellent production.

- Experience designing SDKs, APIs, and data contracts that serve multiple downstream teams.

- Excellent communication skills and the ability to build organizational consensus around platform decisions.

- Collaborative and empathetic working style: listens to understand the needs of scientists, engineers, and downstream teams, and leads through influence.

- Proven track record setting technical strategy and direction for a growing engineering organization, and mentoring engineers in a fast-moving environment.

Why Join Us:

- Own the platform foundation for a category-defining autonomous scientific reasoning engine.

- Take frontier agentic AI from research to dependable production at scale.

- Collaborate with visionary thinkers and top-tier researchers across Flagship’s ecosystem.

- Set the technical standards that the broader platform and product teams build on.

- Shape the future of AI-powered discovery in a role that combines deep engineering excellence with direct human-health impact.

## Skills

### Required
- Computer Science
- Engineering
- workflow orchestration
- event-driven architecture
- cloud-native engineering
- AWS
- infrastructure-as-code
- containerization
- autoscaling

### Nice to have
- agentic AI
- Pydantic AI
- LangGraph
- LangChain
- CrewAI
- AutoGen
- Anthropic
- OpenAI
- Vertex AI
- Amazon Bedrock
- LLM observability
- monitoring tooling
- cost-governance / FinOps

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Source: [Apply at job-boards.greenhouse.io](https://job-boards.greenhouse.io/flagshippioneeringinc/jobs/8584555002?utm_source=yubhub.co&utm_medium=jobs_feed&utm_campaign=apply)