# Research Associate I, CFPS Production

**Company**: Bighatbiosciences
**Location**: San Mateo, CA
**Work arrangement**: onsite
**Experience**: entry
**Job type**: full time
**Salary**: $75,000 - $88,000
**Category**: Lab Science
**Industry**: Healthcare

**Apply**: https://bighatbiosciences.pinpointhq.com/en/postings/26224083-090e-4ce8-8d61-c09ab4ab7a38?utm_source=yubhub.co&utm_medium=jobs_feed&utm_campaign=apply
**Canonical**: https://yubhub.co/jobs/job_cdffb730-d6b

## Description

BigHat Biosciences is seeking a self-motivated individual for a Research Associate, CFPS Production role to manufacture, validate and execute experiments to develop cell-free protein synthesis (CFPS) reagents for BigHat’s high-throughput, automated platform for producing and characterizing antibodies.

## Key Responsibilities

- Manufacture and validate CFPS reagents used in BigHat’s high-throughput antibody screening platform including making buffers, media for biomass production and performing QC experiments on reagents.

- Maintain CFPS reagent manufacturing equipment including incubators, centrifuges, and homogenizers.

- Coordinate with lab ops team to request/order supplies for CFPS reagent manufacturing to ensure reliable stock for platform.

- Design and run experiments for development of next generation CFPS extract to optimize yield and purity of next generation antibodies on our platform.

- Keep a detailed record of all experiments using BigHat’s documentation tools, and clearly communicate results and challenges.

- Present experimental plans and results during regular meetings with manager and science teams.

## Skills, Knowledge & Expertise

- B.S. degree in Biochemistry, Molecular Biology, or related field with 1-2 years of industry experience.

- Experience working with recombinant protein expression from bacterial cultures. Experience with CFPS is highly desired but not required.

- Experience with molecular cloning techniques including primer design, PCR, mutagenesis, Golden Gate Assembly.

- Preferred: Experience and knowledge of protein purification methods including affinity chromatography and SEC.

- Excellent communication skills; organized and works well in small groups.

- Experience with quantitative and/or statistical analysis software is a plus (e.g. Excel, GraphPad Prism, Python, R, etc.)

- Experience with automation and high-throughput tools and robotic instrumentation is a plus.

## Benefits

The salary estimated for this position is $75,000 - $88,000 + bonus + options + benefits. Compensation will vary depending on job-related knowledge, skills, and experience. Actual compensation will be confirmed in writing at the time of the offer.

What BigHat Offers:

- Range of health insurance plan options through Anthem and Kaiser (monthly credit if benefit waived)

- Dental, and vision coverage through Guardian

- Additional well-being benefits through Nayya, OneMedical, Wagmo, Rula, and more

- 401(k) with company match

- DTO, two weeks of company-wide shutdown, and 12 company holidays

- Paid parental leave

## Skills

### Required
- B.S. degree in Biochemistry, Molecular Biology
- recombinant protein expression
- molecular cloning techniques
- communication skills

### Nice to have
- CFPS
- protein purification methods
- quantitative analysis software
- automation and high-throughput tools

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Source: [Apply at bighatbiosciences.pinpointhq.com](https://bighatbiosciences.pinpointhq.com/en/postings/26224083-090e-4ce8-8d61-c09ab4ab7a38?utm_source=yubhub.co&utm_medium=jobs_feed&utm_campaign=apply)