# Research Associate I/II, Bioprocess Development

**Company**: Flagship Pioneering
**Location**: Cambridge, MA
**Work arrangement**: onsite
**Experience**: entry
**Job type**: full-time
**Salary**: $65,000 - $93,500
**Category**: Research
**Industry**: Healthcare

**Apply**: https://job-boards.greenhouse.io/flagshippioneeringinc/jobs/8797916002?utm_source=yubhub.co&utm_medium=jobs_feed&utm_campaign=apply
**Canonical**: https://yubhub.co/jobs/job_cbe789e9-cc0

## Description

We are seeking a highly motivated Research Associate I/II to support the development and optimization of microbial fermentation processes for recombinant protein production.

The ideal candidate is highly hands-on, technically rigorous, and comfortable operating independently in a dynamic research setting. This role requires strong practical experience with bench-scale bioreactors, microbial culture techniques, fermentation analytics, and laboratory operations.

Key Responsibilities:

- Operate, monitor, and troubleshoot shake flask and bench-scale microbial fermentation systems, executing batch and fed-batch experiments in support of process development objectives.

- Prepare media, inoculum, and feed solutions for fermentation runs.

- Set up, sterilize, calibrate, and maintain fermentation reactors.

- Perform routine analytical work, including OD measurements and metabolite analysis.

- Contribute to safe, rigorous laboratory operations.

- Collaborate closely with strain engineering, downstream, and analytical teams to support integrated process development as the platform scales.

Professional Experience & Qualifications:

- Hands-on experience in microbial fermentation, microbiology, bioprocess development, or related laboratory environments

- Experience in operating and maintaining bench-scale bioreactors for microbial fermentation workflows, with strong understanding of aseptic technique and microbial culture handling

- Strong organizational and documentation skills

- Ability to independently execute experiments and troubleshoot routine process issues

Preferred Experience:

- Experience with fed-batch fermentation processes

- Familiarity with HPLC-based analysis of sugars, organic acids, or fermentation metabolites

- Experience with recombinant protein expression systems

- Experience supporting process optimization or scale-up activities

- Familiarity with fermentation data analysis and process monitoring tools

The salary range for this role is $65,000 - $93,500.

## Skills

### Required
- microbial fermentation
- bioprocess development
- bench-scale bioreactors
- microbial culture techniques
- fermentation analytics
- laboratory operations

### Nice to have
- fed-batch fermentation processes
- HPLC-based analysis
- recombinant protein expression systems
- process optimization
- fermentation data analysis

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