# Senior Scientist-Chemical Engineer **Company**: Pfizer **Location**: Bothell **Work arrangement**: onsite **Experience**: senior **Job type**: full-time **Salary**: $93,600.00 to $156,000.00 **Category**: Engineering **Industry**: Healthcare **Apply**: https://pfizer.wd1.myworkdayjobs.com/en-US/PfizerCareers/job/United-States---Washington--Bothell/Sr-Scientist---Chemical-Engineer-for-Drug-Linker_4967217-1?utm_source=yubhub.co&utm_medium=jobs_feed&utm_campaign=apply **Canonical**: https://yubhub.co/job/senior-scientist-chemical-engineer-b2de1b7f-33e/ ## Description At Pfizer, our purpose is to deliver breakthroughs that change patients' lives. Central to this mission is our Research and Development team, which strives to translate advanced science and cutting-edge technologies into impactful therapies and vaccines. We are seeking a highly motivated chemical engineer for the role of Senior Scientist-Chemical Engineer to join our DL Process Development team within Chemical Process and Analytical Development (CPAD) in Bothell, WA. You will join a diverse team responsible for developing Drug Linker (DL) processes for use at manufacturing plants across Pfizer’s network. In this role, you will: - Applies technical and functional engineering knowledge to develop safe, sustainable, robust, scalable, cost-efficient and phase-appropriate processes that are aligned with internal business needs. - Prepare internal research reports and technical presentations summarizing process development activities to capture process knowledge and transfer process understanding to Pfizer’s manufacturing partners. - Lead and/or support purification and isolation process development for internal pre-clinical materials supply. - Design, implement, and interpret data rich experiments independently. - Design experiments to assess scalability of manufacturing processes to ensure successful tech transfer. - Understand unit operation design, process modeling and optimization, process equipment selection, and scale-up methodologies. - Utilize various process modeling approaches to ensure robust tech transfer to pilot and commercial scale facilities. - Assist technology transfer of processes to internal or external clinical and commercial manufacturing sites and external partners. - Collaborate with process chemists and analytical chemists on synthetic strategy and route development. - Develop and implement new technologies for process improvement at external manufacturing partners. - Maintains suitable knowledge on lab data management systems and applies suitable modeling tools to gain process knowledge from data rich experiments. Qualifications: - Applicant must have a bachelor's degree with at least 9+ years of experience; OR a master's degree with more than 7+ years of experience; OR PhD with 0+ years of relevant experience. - Expertise in reaction engineering, including experience developing and validating kinetic models from experimental data. - Excellent knowledge of chemistry and chemical engineering principles and sound understanding of chemical reactor design, thermodynamics, transport phenomena, engineering statistics, and process modeling. - Outstanding laboratory skills, attention to detail, and ability to solve technical problems. - Exceptional interpersonal, multi-disciplinary team collaboration, and communication skills. Nice-to-Have: - Experience with technical transfer of processes into external manufacturing partners. - Experience using Process Analytical Technologies (PAT) such as Raman, FTIR, NIR, on-line HPLC, and FBRM. - Experience with separation processes such as Tangential Flow Filtration (TFF), membrane separation, chromatography purification, or Supercritical Fluid Precipitation/Extraction. - A good foundational understanding of organic chemistry. - Experience building reaction or unit operation models with software such as DynoChem®, Reaction LabTM, ASPEN, gPROMS, VisiMix,, COSMOtherm, and MatLab. - Knowledge and experience applying Design of Experiments. - Strong organization, time management, and problem-solving skills. - A team player with good communication skills, desire to achieve team and individual goals. - Strong technical writing and presentation skills. - Working knowledge of analytical techniques such as HPLC/UPLC, MS, PXRD, DSC, TGA, and NMR. - Applied data science methods, such as machine learning and AI. Benefits: - Comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. - 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution. - Paid vacation, holiday and personal days. - Paid caregiver/parental and medical leave. - Health benefits to include medical, prescription drug, dental and vision coverage. For more fresh new jobs, check out [yubhub.co](https://yubhub.co/). ## Skills ### Required - chemical engineering - reaction engineering - process modeling - chemical reactor design - thermodynamics - transport phenomena - engineering statistics ### Nice to have - Process Analytical Technologies (PAT) - separation processes - Tangential Flow Filtration (TFF) - membrane separation - chromatography purification - Supercritical Fluid Precipitation/Extraction - DynoChem - Reaction LabTM - ASPEN - gPROMS - VisiMix - COSMOtherm - MatLab - Design of Experiments --- Source: [Apply at pfizer.wd1.myworkdayjobs.com](https://pfizer.wd1.myworkdayjobs.com/en-US/PfizerCareers/job/United-States---Washington--Bothell/Sr-Scientist---Chemical-Engineer-for-Drug-Linker_4967217-1?utm_source=yubhub.co&utm_medium=jobs_feed&utm_campaign=apply)