# Senior Translational Scientist

**Company**: GSK
**Location**: Pennsylvania - Upper Providence
**Experience**: senior
**Job type**: full-time
**Category**: Healthcare
**Industry**: Healthcare

**Apply**: https://gsk.wd5.myworkdayjobs.com/en-US/GSKCareers/job/USA---Pennsylvania---Upper-Providence/Senior-Director--Cardiovascular-and-Cardiometabolic-Translational-Biology_450668?utm_source=yubhub.co&utm_medium=jobs_feed&utm_campaign=apply
**Canonical**: https://yubhub.co/jobs/job_af5e3bd6-32c

## Description

We are seeking a Senior Translational Scientist to identify opportunities to develop novel therapies, next-generation translational approaches, human-relevant model systems, and advanced analytical methodologies that accelerate drug discovery and development across cardiovascular and organ dysfunction pathways.

**Responsibilities:**

- Contribute to identification, evaluation, and scientific diligence of business development opportunities, particularly those focused on cardiovascular, vascular, cardio-renal, and cardio-metabolic mechanisms.

- Establish and maintain strategic collaborations with academic institutions, contract research organizations, and external experts to access cutting-edge technologies, unique patient datasets, advanced model systems, and translational capabilities.

- Drive the discovery and advancement of innovative cardiovascular assets while ensuring adherence to relevant policies, regulatory expectations, and quality standards.

- Provide input to portfolio resourcing and external spend planning by defining critical-path experiments and recommending efficient use of internal capabilities and external partners to maximize scientific impact and translational success.

**Requirements:**

- MD/PhD or PhD in a relevant scientific discipline (e.g., Cardiovascular Biology, Cell/Molecular Biology, Genetics, Pharmacology, Immunology, or related field) with extensive experience in preclinical biology and forward and reverse translation.

- Extensive experience in the pharmaceutical or biotechnology industry, with a strong focus on cardiovascular disease, vascular biology, cardio-renal disease, pulmonary vascular disease, heart failure, fibrosis, inflammation, and/or cardiometabolic disease.

- Deep understanding of target mechanisms and translational evidence required to support early clinical development.

- Demonstrated ability to operate as a senior individual contributor and scientific thought leader, influencing decisions in a matrix environment through data-driven recommendations, clear communication, and collaboration.

- Experience leading external scientific collaborations and evaluating business development opportunities.

- Proven track record of advancing targets and/or therapeutic assets through key discovery and early development milestones, including development of fit-for-purpose translational packages encompassing mechanistic rationale, human relevance, biomarker strategy, and clinical hypotheses.

**Preferred Qualifications:**

- Demonstrated achievement as a translational scientist capable of partnering with Disease Area Acceleration Teams, Clinical Research Heads, and Early Development and Medicine Development Leaders to interpret complex datasets, connect preclinical findings to clinical outcomes, and provide recommendations on indication expansion, patient stratification, biomarker strategies, and business development opportunities.

- Deep expertise in cardiovascular pathophysiology, vascular biology, cardio-renal-metabolic syndromes, pulmonary vascular disease, fibrosis, inflammation, and organ dysfunction biology.

- Strong understanding of human genetics, multi-omics, and computational approaches to target identification and validation.

- Strong business acumen and understanding of commercial considerations, patient segmentation, and market opportunities.

- Excellent communication and presentation skills with the ability to influence senior stakeholders internally and externally.

- Demonstrated ability to thrive in a fast-paced environment and manage multiple priorities simultaneously.

- Knowledge of regulatory requirements and compliance standards relevant to translational medicine and pharmaceutical development.

**Benefits:**

- Comprehensive benefits program, including [insert benefits from GSK US Benefits Summary]

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## Skills

### Required
- Biotechnology
- Business Strategies
- Cell Biology
- Cross-Functional Teamwork
- Drug Development
- Drug Discovery Process
- Influencing Without Authority
- Interpersonal Communication
- Life Science
- Market Opportunities
- Matrix Leadership
- Molecular Biology
- Scientific Research
- Scientific Writing
- Strategic Alignment

### Nice to have
- Cardiovascular Biology
- Vascular Biology
- Cardio-Renal-Metabolic Syndromes
- Pulmonary Vascular Disease
- Fibrosis
- Inflammation
- Organ Dysfunction Biology
- Human Genetics
- Multi-Omics
- Computational Approaches

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