# Vice President, Clinical Pharmacology & Pharmacometrics

**Company**: Recursion
**Location**: New York, New York
**Work arrangement**: hybrid
**Experience**: executive
**Job type**: full-time
**Salary**: $353,980 to $443,080
**Category**: Healthcare
**Industry**: Healthcare

**Apply**: https://job-boards.greenhouse.io/recursionpharmaceuticals/jobs/8369673?utm_source=yubhub.co&utm_medium=jobs_feed&utm_campaign=apply
**Canonical**: https://yubhub.co/job/vice-president-clinical-pharmacology-and-ac697dab-f97/

## Description

## Job Summary

As Vice President, Clinical Pharmacology & Pharmacometrics, you will set the enterprise strategy for clinical pharmacology, pharmacometrics, and model-informed drug development across Recursion's advancing clinical portfolio.

## Responsibilities

- Set the enterprise strategy for Clinical Pharmacology, Pharmacometrics, Translational Modeling, and preclinical-to-clinical quantitative integration across Recursion's clinical and post-candidate nomination portfolio

- Own dose strategy from first-in-human planning through registrational development, including dose escalation, dose optimization, exposure-response, safety, efficacy, and label-supporting dose justification

- Lead quantitative development approaches, including population PK, PK/PD, exposure-response, PBPK, QSP, disease progression modeling, and clinical trial simulations

- Design and oversee clinical pharmacology studies, including food effect, DDI, organ impairment, QT/cardiac safety, bioavailability/bioequivalence, mass balance/ADME, and special population studies

- Partner cross-functionally with Clinical Development, Development Sciences, DMPK, Toxicology, Translational Modeling, Biomarkers, Regulatory, Biostatistics, CMC, and Data Science to inform development strategy and decision-making

- Represent Recursion as the clinical pharmacology expert in regulatory interactions and ensure high-quality clinical pharmacology contributions to INDs/CTAs, briefing books, NDAs/BLAs/MAAs, regulatory responses, and labeling

- Represent Clinical Pharmacology and Translational Modeling in cross-functional program teams, governance forums, regulatory interactions, and alliance settings with Recursion's external pharma partners

- Build, mentor, and scale a high-performing Clinical Pharmacology and Pharmacometrics function, including internal talent, consultants, CROs, and external modeling partners

- Advance the responsible use of AI, automation, and advanced analytics to improve evidence integration, modeling workflows, and clinical development decisions

## Requirements

- Advanced degree in clinical pharmacology, pharmacometrics, pharmaceutical sciences, quantitative pharmacology, biomedical engineering, medicine, pharmacy, or a related field; PhD, PharmD, or MD preferred

- 15+ years of biotech or pharmaceutical industry experience, including significant leadership experience in Clinical Pharmacology, Pharmacometrics, Quantitative Pharmacology, or model-informed drug development

- Proven success leading clinical pharmacology strategy across multiple programs, ideally from first-in-human studies through registrational development, submission, and labeling

- Deep expertise in PK, PK/PD, exposure-response, exposure-safety, population PK, PBPK, QSP, dose optimization, dose justification, and model-based clinical trial design

- Experience designing, interpreting, and defending clinical pharmacology studies and analyses in support of global development and regulatory submissions

- Strong understanding of FDA, EMA, MHRA, PMDA, and ICH expectations for clinical pharmacology, pharmacometrics, dose selection, MIDD, and regulatory documentation

- Demonstrated ability to build and lead high-performing teams, influence senior stakeholders, manage external partners, and communicate complex quantitative concepts clearly to executives, program teams, partners, and regulators

- Experience in oncology, rare disease, and/or small molecule development strongly preferred; experience applying AI, advanced analytics, or automation in clinical pharmacology is a plus

## Benefits

- Estimated annual base salary range: $353,980 to $443,080 (New York City, San Francisco Bay Area, & Boston area), $321,800 to $402,800 (all other US locations)

- Annual bonus, equity compensation, and comprehensive benefits package

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## Skills

### Required
- Clinical Pharmacology
- Pharmacometrics
- Quantitative Pharmacology
- Model-Informed Drug Development
- AI
- Automation
- Advanced Analytics

### Nice to have
- Oncology
- Rare Disease
- Small Molecule Development

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