# Research Scientist I/II

**Company**: Freenome
**Location**: Brisbane, California
**Work arrangement**: onsite
**Experience**: senior
**Job type**: full-time
**Salary**: $132,050 - $167,475
**Category**: Research
**Industry**: Healthcare

**Apply**: https://job-boards.greenhouse.io/freenome/jobs/8637480002?utm_source=yubhub.co&utm_medium=jobs_feed&utm_campaign=apply
**Canonical**: https://yubhub.co/jobs/job_a85447d7-164

## Description

At Freenome, you will help develop assay technologies used to analyze patient samples and contribute to the mission of early detection and intervention in human disease.

As a Research Scientist I/II, you will provide experience in next-generation-sequencing (NGS)-based analyses of DNA. You will contribute to the program's technical base by creating and optimizing new next-generation sequencing (NGS) assays and workflows for DNA/RNA, or to the program's scientific base by elevating the understanding of the biological context of these assay signals in cancer.

Responsibilities:

- Independently design and execute experiments to help optimize the performance of Freenome's new or existing assays.

- Prototype new next-generation sequencing (NGS) methods, optimize the performance of existing assays, and execute biomarker discovery studies on clinical samples.

- Assist with project planning and timeline generation and work with cross-functional teams to coordinate tasks within and across projects.

- Take detailed notes, gather high-quality data, and openly communicate on lessons learned while performing experiments.

- Independently troubleshoot workflows and understand the rationale behind workflow optimization choices.

- Help with process improvements across the lab by thinking critically about the execution of all experiments.

- Perform advanced analysis and data visualization of results to answer experimental questions and guide next steps.

- Prepare and present experiment or project results at internal meetings, with clear articulation of goals, results, conclusions, and how results presented fit into broader project.

Requirements:

- PhD in molecular biology, biochemistry, genetics, or a related field or Bachelor's or Master's with 8+ years experience post-Bachelor's in the life sciences (industry and/or academia).

- Hands-on experience with and expert-level knowledge in NGS-based workflows including sample preparation, library preparation, target capture, and sequencing.

- Biological understanding of human cell-free nucleic acids, single-cell analysis methods, immunology, and/or cancer biology.

- Ability to perform advanced data analysis and critically examine experimental results.

- Proven track record of designing and running successful experiments, preparing data for review, and giving effective scientific presentations.

- Clear and proactive communication skills and ability to collaborate effectively with team members in the same and adjacent disciplines.

- Flexible and highly motivated to learn new skills and comfortable adapting to changing priorities.

Nice to haves:

- Ability to perform bioinformatic analysis in a scientific programming language (e.g., Python or R).

- Experience handling and preparing blood and/or tissue samples.

- Experience running high-throughput experimental designs and/or assays on an automated liquid handling platform.

- Experience using ELN (electronic lab notebook) and LIMS (lab information management system).

Benefits:

- The US target range of our base salary rate for new hires is $132,050 - $167,475.

- You will also be eligible to receive equity, cash bonuses, and a full range of medical, financial, and other benefits depending on the position offered.

## Skills

### Required
- molecular biology
- biochemistry
- genetics
- NGS-based workflows
- data analysis
- scientific presentations

### Nice to have
- bioinformatic analysis
- Python
- R
- blood and/or tissue samples
- high-throughput experimental designs
- ELN
- LIMS

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Source: [Apply at job-boards.greenhouse.io](https://job-boards.greenhouse.io/freenome/jobs/8637480002?utm_source=yubhub.co&utm_medium=jobs_feed&utm_campaign=apply)