# Research Associate I/II

**Company**: Freenome
**Location**: Brisbane, California
**Work arrangement**: onsite
**Experience**: entry
**Job type**: full-time
**Salary**: $37.68 - $46.69
**Category**: Research
**Industry**: Healthcare

**Apply**: https://job-boards.greenhouse.io/freenome/jobs/8637437002?utm_source=yubhub.co&utm_medium=jobs_feed&utm_campaign=apply
**Canonical**: https://yubhub.co/jobs/job_a368ee95-84f

## Description

At Freenome, you will help develop assay technologies used to analyse patient samples and contribute to the mission of early detection and intervention in human disease.

As a Research Associate I/II, you will provide experience in next-generation-sequencing (NGS)-based analyses of DNA. Starting with a prototype assay, you will contribute to developing and validating clinical-grade assays to measure complex, blood-based analytes.

You will work closely with multiple teams including molecular research, computational science, automation engineering, and clinical operations to develop assays in a regulated, high-throughput environment. You will also identify ways to rapidly iterate and improve on existing methods to evaluate technologies that can enhance end-to-end test performance.

The role reports to the Senior Manager and Staff Research Scientist. This role will be an onsite role.

**Responsibilities**

- Apply knowledge of molecular biology, nucleic-acid biochemistry, and next-generation sequencing to develop assays for DNA.

- Characterise automated assays by generating and analysing experimental data.

- Gather high-quality data, take detailed notes, and openly communicate on lessons learned while performing experiments.

- Collaborate with research teams and computational biologists, understand how data reflect underlying molecular biology, and contribute to analysing data and generating study conclusions.

- Present data in cross-functional teams.

- Participate in troubleshooting efforts and design experiments with some supervisor guidance.

- Help with process improvements across the lab by thinking critically about the execution of all experiments.

**Requirements**

- Bachelor's degree with 1+ years of relevant industry experience or Master's degree in molecular biology, or a related field.

- Hands-on experience in NGS-based assay development including sample preparation, library preparation, target capture, and sequencing.

- Biological understanding of human cell-free nucleic acids, single-cell analysis methods, immunology, and/or cancer biology.

- High attention to detail and ability to record accurate and detailed observations, assess impact, and perform troubleshooting as required.

- Flexible and highly motivated to learn new skills and comfortable adapting to changing priorities.

- Ability to manually pipette with high confidence, accuracy, and precision.

- Clear and proactive communication skills and ability to collaborate effectively with team members in the same and adjacent disciplines.

**Nice to Have**

- Experience working in a regulated laboratory environment (CLIA, GLP/GCLP, IVD development).

- Experience with automated platforms in plate-based, low-volume formats and/or microfluidics and experience working with automated liquid handlers.

- Experience using ELN (electronic lab notebook) and LIMS (lab information management system).

- Familiarity with programming in a scientific programming language (e.g., Python or R).

**Benefits**

- The US target range of our base hourly rate for new hires is $37.68 - $46.69.

- You will also be eligible to receive equity, cash bonuses, and a full range of medical, financial, and other benefits depending on the position offered.

## Skills

### Required
- molecular biology
- nucleic-acid biochemistry
- next-generation sequencing
- NGS-based assay development
- sample preparation
- library preparation
- target capture
- sequencing

### Nice to have
- regulated laboratory environment
- automated platforms
- plate-based formats
- microfluidics
- automated liquid handlers
- ELN
- LIMS
- Python
- R

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Source: [Apply at job-boards.greenhouse.io](https://job-boards.greenhouse.io/freenome/jobs/8637437002?utm_source=yubhub.co&utm_medium=jobs_feed&utm_campaign=apply)
