# Associate Principal Scientist, Liquid Chromatography-Mass Spectrometry (LCMS) Assay Development

**Company**: IQVIA Laboratories
**Location**: Ithaca, New York
**Work arrangement**: onsite
**Experience**: senior
**Job type**: full-time
**Salary**: $83,000.00 - $173,000.00
**Category**: Research
**Industry**: Healthcare

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## Description

We are seeking 2 Associate Principal Scientists, Liquid Chromatography-Mass Spectrometry (LCMS) Assay Development to join IQVIA Laboratories at Ithaca, NY.

The Associate Principal Scientist, Liquid Chromatography-Mass Spectrometry Assay Development will develop rugged and challenging bioanalytical methods, support method hand-off, and troubleshoot complex assay development challenges. This role will strengthen small and large molecule analysis capabilities through advanced extraction, chromatographic, and mass spectrometric techniques.

**Responsibilities**

- Develop reliable extraction, chromatographic, and mass spectrometric analysis procedures for highly challenging and complex methods

- Document all project work according to Assay Development processes and procedures

- Communicate progress and status to the Director of Assay Development and Project Management, as necessary

- Present method development results at Prevalidation Committee Meetings

- Independently interact with Project Management and clients to provide project status updates, as necessary

- Guide Wet Lab staff through clear instructions and communication

- Provide clear method documentation to Project Management and support analytical staff during the method hand-off process

- Actively contribute to conference presentations and publications under PK/PD and biomarker analysis

**Requirements**

- Master's Degree with 6-8 years' experience, or Ph.D. 2-5 yrs experience (industry experience preferred)

- Highly experienced in Liquid Chromatography-Mass Spectrometry and biologic sample preparation

- Advanced knowledge of chemistry involved in method development procedures

- Experience with regulated bioanalysis, method development, LBA/Liquid Chromatography-Mass Spectrometry, proteomics sample preparation, and automation

- Other Equivalent combination of education, training, and experience may be accepted in lieu of degree

**The Knowledge, Skills and Abilities Needed for This Role**

- Advanced knowledge in Liquid Chromatography-Mass Spectrometry theory and biologic sample preparation

- Knowledge of high resolution mass spectrometry, including Thermo Orbitraps, Exploris, and Excedions

- Knowledge of triple quadrupole systems, including Sciex 6500, 6500 plus, and 7500 plus

- Hands-on experience with clinical biomarker analysis

- Ability to develop and present well-organized Prevalidation Committee Meeting presentations

- Excellent attention to detail and communication skills

**What We Offer You**

- Competitive salary: $83,000.00 - $173,000.00 per year

- Comprehensive benefits program to support physical, mental and emotional, financial and social well-being

## Skills

### Required
- Liquid Chromatography-Mass Spectrometry
- biologic sample preparation
- regulated bioanalysis
- method development
- LBA/Liquid Chromatography-Mass Spectrometry
- proteomics sample preparation
- automation
- Thermo Orbitraps
- Exploris
- Excedions
- Sciex 6500
- Sciex 6500 plus
- Sciex 7500 plus

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