# AI Portfolio Lead

**Company**: Pfizer
**Location**: San Diego, California
**Work arrangement**: hybrid
**Experience**: senior
**Job type**: full-time
**Salary**: $176,600.00 to $294,300.00
**Category**: Research
**Industry**: Healthcare

**Apply**: https://pfizer.wd1.myworkdayjobs.com/en-US/PfizerCareers/job/United-States---California---San-Diego/AI-Oncology-Portfolio-Lead--Director-_4964531-3?utm_source=yubhub.co&utm_medium=jobs_feed&utm_campaign=apply
**Canonical**: https://yubhub.co/job/ai-portfolio-lead-96a6a02b-944/

## Description

As an AI-enabled strategic scientific leader, you will partner with Oncology Research Leadership to integrate AI-driven strategies that will drive data-informed decision-making across Pfizer's Oncology Research pipeline.

You will bridge cutting-edge AI/advanced analytics with deep Oncology R&D expertise to guide portfolio strategy.

Working as an individual contributor reporting into the Head, Portfolio Strategy and Program Management, you will analyze and continuously assess Oncology Research projects using AI-driven insights (predictive models, scenario simulations, competitive intelligence) and propose actionable strategies to Oncology Research Leadership.

Your work will directly inform pipeline prioritization and resource allocation decisions, enhancing the quality and objectivity of governance deliberations with robust data.

### Responsibilities

- Continuously analyze the oncology Research portfolio (ESD through Preclinical) using advanced AI/ML tools and analytics to evaluate each program's scientific strength, probability of success, and strategic portfolio fit per disease area strategies.

- Develop and propose data-driven portfolio strategies (at both project and portfolio levels) to senior leaders and Research governance committee.

- Integrate AI-derived insights into project team and governance discussions, ensuring decisions are based on comprehensive evidence.

- Collaborate closely with discovery research leaders, translational scientists, clinical development teams, and business/strategy functions to synthesize cross-domain data into unified portfolio recommendations.

- Act as the subject matter expert on AI in R&D strategy, championing adoption of advanced analytics and decision intelligence tools.

- Prepare and present high-impact reports that distill complex analyses into clear, actionable insights for senior stakeholders.

- Stay current with emerging AI technologies, industry best practices in portfolio management leveraging AI, and oncology scientific developments.

### Minimum Qualifications

- PhD in a relevant scientific field (e.g., oncology, molecular biology, pharmacology, computational biology) and 5+ years of experience using AI to solve drug discovery problems.

- Experience working with AI/ML teams or implementing AI tools in R&D processes.

- Strong understanding of Oncology R&D workflows and the role of data and AI in scientific and clinical decision making.

- 10+ years of experience in pharmaceutical/biotech R&D, including direct involvement in drug discovery or development and strategic roles.

- Deep understanding of drug discovery and development processes across multiple modalities (small molecules, biologics, and ADCs) and oncology therapeutic area knowledge.

### Preferred Qualifications

- Formal training or hands-on experience in data science, bioinformatics, or AI-driven decision support in a life sciences context.

- Broad exposure to multiple R&D domains (discovery, preclinical, clinical, translational, business development).

- Experience championing new approaches or technologies within an organization, driving cultural adoption of data-driven decision-making.

### Benefits

- Comprehensive and generous benefits and programs to help colleagues lead healthy lives and support each of life's moments.

- 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution.

- Paid vacation, holiday, and personal days.

- Paid caregiver/parental and medical leave.

- Health benefits, including medical, prescription drug, dental, and vision coverage.

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## Skills

### Required
- AI
- ML
- data analysis
- oncology
- R&D
- strategic planning

### Nice to have
- data science
- bioinformatics
- AI-driven decision support

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Source: [Apply at pfizer.wd1.myworkdayjobs.com](https://pfizer.wd1.myworkdayjobs.com/en-US/PfizerCareers/job/United-States---California---San-Diego/AI-Oncology-Portfolio-Lead--Director-_4964531-3?utm_source=yubhub.co&utm_medium=jobs_feed&utm_campaign=apply)