# Director, Real-World Evidence & Health Outcomes (RWE-HO), mRNA Vaccines

**Company**: GSK
**Location**: Pennsylvania - Upper Providence
**Experience**: senior
**Job type**: full-time
**Salary**: $203,775 to $339,625
**Category**: Healthcare
**Industry**: Healthcare

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## Description

The Director, Real-World Evidence & Health Outcomes (RWE-HO), mRNA Vaccines will provide scientific and strategic leadership for the development and delivery of real-world evidence supporting GSK's mRNA vaccine portfolio, with a primary focus on influenza.

Responsibilities:

- Lead and contribute to the integrated RWE-HO strategy for mRNA influenza vaccines, aligned with clinical development, medical, regulatory and commercialization priorities.

- Translate strategic evidence gaps into clear research questions and fit-for-purpose study designs across pre-launch, launch and post-marketing phases.

- Provide expert scientific input to governance decisions, investment choices, evidence prioritization and risk mitigation.

- Lead the design, implementation and interpretation of post-marketing influenza vaccine effectiveness studies in the United States and other geographies.

- Ensure studies meet appropriate standards of scientific rigor, transparency, reproducibility and fitness for their intended decision-making purpose.

- Build productive collaborations with US academic investigators, healthcare systems, data partners and vaccine effectiveness research networks.

- Partner effectively with Clinical Development, Epidemiology, Medical Affairs, Regulatory, Safety, Biostatistics, Market Access, Data Science and Commercial teams.

- Lead multiple complex projects, budgets and external research collaborations, ensuring quality, timely delivery and appropriate escalation of risks.

- Influence senior stakeholders without direct authority and communicate complex epidemiological concepts in a clear, decision-focused manner.

- Mentor colleagues and contribute to strengthening RWE-HO capabilities, standards and innovation across the organization.

Basic Qualifications:

- PhD, ScD, DrPH, MD, PharmD, MPH or equivalent advanced degree in epidemiology, public health, pharmacoepidemiology, health outcomes research or a related quantitative discipline.

- 5+ years experience in real-world evidence, epidemiology or health outcomes research within the pharmaceutical or vaccine industry, academia, public health or a comparable environment.

- Experience designing, conducting and interpreting post-marketing vaccine studies in the United States.

- Research experience with vaccine effectiveness studies.

- Experience using large US healthcare databases, including administrative claims, electronic health records or linked real-world datasets.

- Experience leading complex studies from concept through delivery, interpretation and scientific dissemination.

- Demonstrated effectiveness in global, cross-functional matrix teams and in managing internal and external stakeholders.

Preferred Qualifications:

- Direct experience with influenza vaccine effectiveness studies in the United States.

- Experience with US Medicare, commercial claims, EHR and linked claims/EHR data.

- Knowledge of US influenza vaccination recommendations, vaccine delivery and healthcare systems.

- Experience studying severe influenza, hospitalization, cardiovascular complications or other downstream outcomes.

- Experience leading global evidence-generation plans or multi-country observational studies.

What success looks like: The successful candidate will combine deep technical expertise with strategic asset-level thinking. They will design credible US post-marketing studies, anticipate the methodological challenges specific to influenza, and convert complex evidence needs into practical solutions. They will be a trusted scientific partner who can influence decisions, build external credibility and deliver evidence that supports the value and appropriate use of GSK's mRNA vaccines.

## Skills

### Required
- Epidemiology
- Health Outcomes Research
- Real-World Evidence
- Influenza Vaccine Effectiveness Studies
- US Healthcare Databases
- Cross-Functional Leadership

### Nice to have
- US Medicare
- Commercial Claims
- EHR and Linked Claims/EHR Data
- US Influenza Vaccination Recommendations

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