# Senior Scientist, Target ID, Immunology Cell Therapy Discovery

**Company**: Immunology Discovery Group
**Location**: Waltham, Massachusetts, United States of America
**Work arrangement**: onsite
**Experience**: senior
**Job type**: full-time
**Salary**: $116,284.00 - $174,426.00
**Category**: Engineering
**Industry**: Healthcare

**Apply**: https://astrazeneca.eightfold.ai/careers/job/563877689867501
**Canonical**: https://yubhub.co/jobs/job_89b1cd26-eed

## Description

We are seeking a dedicated, hands-on Scientist or Senior Scientist to join our Immunology Cell Therapy Discovery team.

The role centers on novel target identification and validation for cell therapy discovery initiatives, underpinned by an in-depth understanding of cellular and molecular immunology, pathology of inflammation and immune disorders and/or expertise in CAR-T engineering.

Key responsibilities include: Demonstrating a comprehensive understanding of immunopathology at the cellular and molecular levels; multi-omics and bioinformatic data analysis; the landscape of known drug targets and therapeutics across modalities in clinical use; and emerging targets with investigational therapeutics in the field.

Partnering with cross-functional teams to initiate and drive discovery efforts focused on immune disorders, ensuring adherence to all relevant laws, regulations, and company policies related to the development and delivery of medicines.

Initiating cell therapy research,guided by curiosity, hypothesis, and data,to assess and validate novel targets, strategies, and approaches, enabling robust decision-making.

Essential skills and experience include: Advanced degree in Immunology, virology, innate and adaptive immune response, molecular or cell biology, bioengineering, or a related field; demonstrated proficiency in T- and B-cell culture and functional assays; multicolor flow cytometry (analysis and sorting); bioinformatics; in vivo disease models; and CRISPR and other genome-editing technologies.

Desirable experience includes a track record of peer-reviewed publications in prestigious immunological journals and/or patents.

## Skills

### Required
- immunopathology
- multi-omics
- bioinformatic data analysis
- drug targets
- investigational therapeutics
- cell therapy research
- CRISPR
- genome-editing technologies

### Nice to have
- publication record
- patent