# Sr Director Therapeutic Area (Hepatology)- US- Remote

**Company**: ICON plc
**Location**: Cambridge, MA
**Work arrangement**: remote
**Experience**: senior
**Job type**: full-time
**Salary**: $195,808.00-$244,760.00
**Category**: Healthcare
**Industry**: Healthcare

**Apply**: https://icon.wd3.myworkdayjobs.com/en-US/broadbean_external/job/US-Cambridge-MA/Senior-Director--Drug-Development-Services--Cardiometabolic-_JR160886?utm_source=yubhub.co&utm_medium=jobs_feed&utm_campaign=apply
**Canonical**: https://yubhub.co/jobs/job_7a6fb480-5e5

## Description

ICON is seeking a Senior Director, Drug Development & Consulting – Cardiometabolic to join their team in a highly visible, client-facing role.

This position offers the opportunity to act as a trusted advisor to senior stakeholders across the industry, including CEOs, CMOs, and other Cardiometabolic Therapeutic Area Heads.

**The Role**

This is a consultative and advisory role where you will serve as a key scientific partner to both external clients and internal teams.

**Key Responsibilities**

- Lead strategic Cardiometabolic drug development design, delivering tailored, asset-focused solutions across liver diseases including MASLD/MASH, alcohol-associated liver disease (ALD), cirrhosis, viral hepatitis, and other chronic and rare liver conditions like PBC, PSC, PFIC

- Own end-to-end protocol development, including design, scientific review, and evaluation for Cardiometabolic clinical trials across Phases I–IV

- Partner directly with senior client stakeholders (e.g., CMO, TA Heads, Clinical Development leadership) to provide expert guidance on Cardiometabolic development strategy and data interpretation

- Act as scientific and strategic lead in proposal development, study strategy, and bid defense activities within Cardiometabolic

- Build and maintain strong relationships with Cardiometabolic key opinion leaders (KOLs), advisory boards, and relevant regulatory authorities

- Contribute to the development of Cardiometabolic-focused service offerings, supporting innovation and growth in liver disease drug development capabilities

- Provide training, mentorship, and thought leadership in Cardiometabolic to internal teams and external partners

- Participate in portfolio reviews, governance discussions, and scientific oversight of Cardiometabolic programs

- Support operational teams with high-level scientific input, including investigator meetings and Cardiometabolic-specific study discussions

- Represent the organization at Cardiometabolic congresses and scientific forums to promote clinical excellence and scientific leadership

**What You Bring**

- Deep, recognized expertise in Cardiometabolic and liver disease drug development

- Strong understanding of Cardiometabolic clinical trial design, biomarkers, endpoints (e.g., fibrosis staging, histologic and non-invasive markers), and evolving therapeutic landscapes (e.g., MASLD/MASH, alcohol-associated liver disease (ALD), cirrhosis, immuno-Cardiometabolic approaches and antiviral therapies)

- Proven ability to operate in a strategic, client-facing, consultative environment within pharmaceutical or clinical research settings

- Experience engaging and influencing senior scientific and clinical stakeholders across industry and academia

- Excellent communication and presentation skills, with the ability to translate complex Cardiometabolic data into clear, actionable development insights

- Collaborative, global mindset with strong cross-functional leadership capability

- MD required, ideally with specialization or substantial clinical/research experience in Cardiometabolic diseases

**Additional Information**

- 20- 40% travel (domestic and international)

- Opportunity to work in a highly visible, impact-driven role shaping the future of Cardiometabolic drug development

**Rewards & Benefits**

- Competitive base salary and performance related incentives

- Health and wellbeing programmes including medical, dental, and vision coverage where applicable

- Retirement and pension plans

- Life assurance and disability coverage

- Employee assistance programmes and wellbeing resources

- Learning and development opportunities through structured training and career pathways

## Skills

### Required
- Cardiometabolic
- liver disease
- drug development
- clinical trials
- scientific leadership

---

Source: [Apply at icon.wd3.myworkdayjobs.com](https://icon.wd3.myworkdayjobs.com/en-US/broadbean_external/job/US-Cambridge-MA/Senior-Director--Drug-Development-Services--Cardiometabolic-_JR160886?utm_source=yubhub.co&utm_medium=jobs_feed&utm_campaign=apply)