# Operations Engineer/ Production Scientist - Peptide Manufacturing **Company**: Hims & Hers **Location**: Menlo Park, California **Work arrangement**: onsite **Experience**: mid **Job type**: Full time **Salary**: $110K – $125K **Category**: Operations **Industry**: Healthcare **Apply**: https://jobs.ashbyhq.com/hims-and-hers/f2028c9a-adc0-49aa-a25f-74e9769593fc?utm_source=yubhub.co&utm_medium=jobs_feed&utm_campaign=apply **Canonical**: https://yubhub.co/jobs/job_66b8cace-66e ## Description We are seeking an Operations Engineer / Production Scientist to support peptide manufacturing at our Menlo Park site. This role will serve as a technical process owner on the manufacturing floor, with a primary focus on Solid-Phase Peptide Synthesis (SPPS), synthesis, cleavage, purification, and lyophilization. You will be responsible for monitoring, analyzing, troubleshooting, and continuously improving peptide manufacturing processes. **Responsibilities:** - Serve as a technical process owner for peptide manufacturing operations, including SPPS, purification, and lyophilization. - Support manufacturing teams during batch execution and provide real-time technical troubleshooting on the floor. - Monitor critical process parameters and key performance indicators across peptide manufacturing processes. - Collect, analyze, and trend manufacturing data to identify process variability, yield losses, bottlenecks, and improvement opportunities. - Develop and maintain manufacturing dashboards tracking yield, cycle time, solvent usage, throughput, batch success rate, and right-first-time metrics. - Evaluate coupling efficiency, resin performance, deprotection efficiency, impurity formation trends, and other process indicators related to SPPS performance. - Identify and implement improvements to reaction conditions, cycle parameters, manufacturing practices, and process controls. - Lead initiatives to improve product yield, throughput, cycle time, overall equipment effectiveness, and process robustness. - Apply Lean Manufacturing, Six Sigma, statistical analysis, and structured root cause analysis tools to reduce waste and process variation. - Lead or support investigations related to process excursions, atypical results, yield losses, manufacturing deviations, and equipment/process issues. - Use tools such as Fishbone Analysis, 5 Why Analysis, FMEA, and Statistical Process Control to identify root cause and drive corrective actions. - Author and revise SOPs, Master Batch Records, process descriptions, manufacturing instructions, technical reports, and process performance summaries. - Support deviation investigations, CAPAs, change controls, risk assessments, process validation, and continued process verification activities. - Ensure technical documentation is accurate, complete, and compliant with cGMP requirements. - Partner cross-functionally with Operations, Engineering, Quality, Supply Chain, and site leadership to improve manufacturing performance. - Support implementation of new equipment, technologies, and manufacturing systems. - Participate in production planning, operational excellence reviews, and process improvement meetings. - Provide technical mentoring and training to manufacturing personnel on process understanding and best practices. **Requirements:** - Bachelor’s degree in Chemical Engineering, Chemistry, Biochemistry, Pharmaceutical Sciences, Biotechnology, or a related field. - 3–7 years of experience in pharmaceutical, biotechnology, peptide manufacturing, API manufacturing, or related chemical processing environments. - Hands-on experience supporting GMP manufacturing operations, investigations, and process validation activities. - Direct experience with Solid-Phase Peptide Synthesis. - Experience analyzing manufacturing process data and implementing process improvements. - Strong technical troubleshooting skills with the ability to identify root cause and implement sustainable corrective actions. - Experience authoring or revising GMP documentation, including SOPs, batch records, technical reports, deviation investigations, CAPAs, change controls, or risk assessments. - Strong cross-functional collaboration skills and the ability to work closely with Manufacturing, Quality, Engineering, and Supply Chain teams. - Clear communication skills with the ability to translate technical process observations into actionable recommendations. **Nice to Have:** - Master’s degree or Ph.D. in Chemical Engineering, Chemistry, Biochemistry, Pharmaceutical Sciences, Biotechnology, or a related field. - Experience in commercial-scale peptide manufacturing. - Experience with process monitoring, Statistical Process Control, and process capability assessments. - Lean Six Sigma Green Belt or Black Belt certification. - Experience using statistical software and data analysis tools such as Minitab, Power BI, Excel advanced analytics, or similar tools. - Experience in a startup or rapidly growing manufacturing organization. **Benefits:** - Competitive salary & equity compensation for full-time roles - Unlimited PTO, company holidays, and quarterly mental health days - Comprehensive health benefits including medical, dental & vision, and parental leave - Employee Stock Purchase Program (ESPP) - 401k benefits with employer matching contribution - Offsite team retreats ## Skills ### Required - Solid-Phase Peptide Synthesis - GMP manufacturing operations - process validation activities - manufacturing process data analysis - technical troubleshooting - GMP documentation - cross-functional collaboration ### Nice to have - Master’s degree or Ph.D. in Chemical Engineering - commercial-scale peptide manufacturing - Statistical Process Control - Lean Six Sigma Green Belt or Black Belt certification - statistical software and data analysis tools --- Source: [Apply at jobs.ashbyhq.com](https://jobs.ashbyhq.com/hims-and-hers/f2028c9a-adc0-49aa-a25f-74e9769593fc?utm_source=yubhub.co&utm_medium=jobs_feed&utm_campaign=apply)