# Senior Physician Leader **Company**: GSK **Work arrangement**: hybrid **Experience**: senior **Job type**: full-time **Salary**: $242,550 to $404,250 **Category**: Healthcare **Industry**: Healthcare **Apply**: https://gsk.wd5.myworkdayjobs.com/en-US/GSKCareers/job/UK--London--New-Oxford-Street/Senior-Medical-Director--Oncology-Clinical-Development---Lung_449575-2?utm_source=yubhub.co&utm_medium=jobs_feed&utm_campaign=apply **Canonical**: https://yubhub.co/jobs/job_65db3b14-34e ## Description We are seeking a Senior Physician Leader to serve as a senior medical expert within the clinical programme, providing medical oversight and clinical insight across study design, conduct, and data interpretation. **Responsibilities:** - Serve as a senior physician leader within the clinical programme, providing medical oversight and clinical insight across study design, conduct, and data interpretation - Provide guidance on medical monitoring and safety oversight across studies, ensuring consistent application of clinical judgement and patient safety standards - Interpret complex clinical and safety data, generating insights that inform programme-level decisions led by the CDL - Partner with the Senior Scientist and cross-functional teams to ensure medical considerations are integrated across study execution and programme delivery - Provide senior medical input into protocol development and study design, ensuring clinical relevance and patient-centred design within the clinical strategy defined by the CDL - Serve as a senior member of the CMT, influencing study-level and programme-level decision-making - Engage with investigators, Key External Experts (KEEs), and scientific leaders to support external engagement and represent the programme at advisory boards, steering committees, and scientific forums - Provide medical guidance and mentorship to Medical Directors within the programme, supporting consistency and development of clinical capability **Detailed Responsibilities:** ### Medical Monitoring and Safety Oversight - Guide interpretation of safety data in collaboration with pharmacovigilance, supporting signal detection, escalation, and benefit–risk evaluation across the programme - Participate in and contribute to safety review forums (e.g., SRT, IDMC), providing senior physician perspective on complex safety questions - Ensure medical monitoring approaches are aligned across studies and consistent with regulatory and organisational standards ### Study Design and Execution - Provide senior medical input into protocol development across studies, ensuring clinical relevance, feasibility, and alignment with the clinical strategy defined by the CDL - Guide clinical aspects of study design and protocol implementation, particularly for complex, high-risk, or multi-study programmes - Support resolution of complex medical questions arising during study conduct, applying clinical judgement to inform programme-level decision-making - Ensure consistency of medical considerations across multiple studies within the programme ### Data Interpretation and Scientific Contribution - Interpret complex clinical data across studies, integrating findings to inform programme-level insights on safety, efficacy, and patient impact - Contribute to programme-level data interpretation and support CDL-led benefit–risk assessment and clinical positioning - Guide development of scientific communications, including publications, congress materials, and clinical summaries - Maintain deep understanding of disease biology, evolving treatment paradigms, and competitive landscape to inform clinical interpretation and programme strategy ### Regulatory and External Engagement - Contribute senior medical expertise to regulatory interactions and Health Authority discussions, including responses to complex clinical and safety queries - Represent the programme at advisory boards, steering committees, and external scientific forums, providing senior physician perspective on clinical data and programme direction - Engage with KEEs and scientific collaborators to support programme development, scientific exchange, and external credibility - Lead or contribute to the clinical and technical diligence assessment of business development opportunities ### Cross-Functional Collaboration and Clinical Matrix Team - Serve as a senior member of the Clinical Matrix Team (CMT), influencing cross-functional alignment and programme-level decision-making - Contribute medical expertise to disease area strategy, integrated evidence planning, and Medical Affairs discussions - Collaborate across functions to ensure alignment on safety, data interpretation, and clinical positioning across the programme - Lead or contribute to Oncology Clinical Development-wide initiatives and workstreams ### People Leadership & Capability Development - Provide oversight, guidance, and mentorship to Medical Directors within the programme, supporting consistency and quality of medical input across studies - Support development of clinical capability within the medical team, including coaching on medical monitoring, data interpretation, and external engagement - Contribute to talent development, performance discussions, and capability building within Oncology Clinical Development **Requirements:** - Medical degree and completion of advanced specialty training, fellowship or country-equivalent higher-level qualification in oncology or haematology - Experience leading lung cancer drug development, including early phase trials - Clinical and pharmaceutical experience in oncology clinical development, with depth across multiple studies or programmes - Experience in medical monitoring, safety evaluation, and clinical data interpretation across clinical studies - Understanding of clinical development processes, GCP, ICH guidelines, and global regulatory frameworks - Experience operating within cross-functional matrix teams and contributing to complex clinical and programme-level decisions ## Skills ### Required - Analytical Thinking - Change Management - Clinical Research - Clinical Trial Designs - Communication - Decision Making - Fostering Collaboration - Influencing Without Authority - Leadership - Matrix Leadership - People Management - Risk Management - Strategic Thinking - Strategy Development - Teamwork ### Nice to have - Deep expertise in lung cancer - Strong scientific communication and stakeholder engagement skills - Deep experience in oncology clinical development across multiple studies or programmes - Experience contributing to or leading aspects of regulatory interactions - Demonstrated experience engaging with KEEs, advisory boards, and scientific communities in oncology - Track record of scientific publications and congress presentations - Deep understanding of oncology disease biology and the evolving treatment landscape --- Source: [Apply at gsk.wd5.myworkdayjobs.com](https://gsk.wd5.myworkdayjobs.com/en-US/GSKCareers/job/UK--London--New-Oxford-Street/Senior-Medical-Director--Oncology-Clinical-Development---Lung_449575-2?utm_source=yubhub.co&utm_medium=jobs_feed&utm_campaign=apply)