# Senior Principal Engineer – Data Engineering, AI & Healthcare Analytics

**Company**: GSK
**Location**: Bengaluru
**Experience**: senior
**Job type**: full-time
**Category**: Engineering
**Industry**: Healthcare

**Apply**: https://gsk.wd5.myworkdayjobs.com/en-US/GSKCareers/job/Bengaluru-Luxor-North-Tower/Senior-Principal-Engineer--Data_448760?utm_source=yubhub.co&utm_medium=jobs_feed&utm_campaign=apply
**Canonical**: https://yubhub.co/jobs/job_30b50a19-3b7

## Description

We are seeking a highly skilled Senior Principal Engineer – Data Engineering, AI & Healthcare Analytics to architect and lead enterprise-scale data lake platforms at GSK.

This is a hands-on technical architect role at the intersection of Azure cloud data engineering, metadata-driven intelligence, AI/ML frameworks, agentic AI systems, and healthcare domain expertise.

You will design and own end-to-end ingestion, quality, and observability frameworks, infuse autonomous AI agents into data pipelines, and partner with clinical, commercial, and research stakeholders to deliver measurable value from GSK’s healthcare data assets.

**Azure Data Engineering & Platform:**

- Lead the design and delivery of scalable Azure Services, Databricks, and enterprise Data Lakehouse solutions supporting patient, commercial, and healthcare data.

- Design resilient batch, incremental, CDC, API, file-based, and real-time pipelines using ADF, Databricks, ADLS, Key Vault, Delta Lake, Apache Iceberg , Unity Catalog, Event Hubs, and Azure integration services.

- Provide end-to-end technical leadership for bidirectional integrations between Salesforce PMP (Patient Management Services) and Data Lake, covering data extraction, transformation, synchronization, reconciliation, schema evolution, error handling, and downstream consumption.

- Provide hands-on technical expertise across the Salesforce ecosystem, including Apex, SOQL, REST/Bulk APIs, authentication, integration patterns, and API development to enable secure and scalable Salesforce PMP integrations.

- Define scalable Salesforce integration patterns using Salesforce APIs, Bulk API, platform events, incremental processing, and API throttling controls.

- Drive Databricks performance engineering through Spark optimization, cluster and job sizing, Photon, caching, file compaction, data layout optimization, and workload monitoring.

- Implement secure access patterns using Unity Catalog, Microsoft Entra ID groups, RBAC, managed identities, service principals, Key Vault, encryption, column masking, and row-level controls.

- Drive Infrastructure-as-Code and automated deployments using Terraform/Bicep, Databricks Asset Bundles, GitHub Actions or Azure DevOps, and environment-specific configuration management.

**Enterprise Data Engineering Capabilities:**

- Design and drive metadata-driven enterprise capabilities for data ingestion, validation, monitoring, and automation.

- Establish reusable, configuration-driven patterns that accelerate data onboarding and adoption across teams.

- Leverage AI/ML and LLM capabilities to enhance metadata management, anomaly detection, mapping, and automated data controls.

- Enable standardized data observability, quality monitoring, alerting, and operational controls.

- Ensure capabilities are scalable, reusable, governed, auditable, and compliant with enterprise standards.

- Drive adoption as shared enterprise capabilities, reducing duplicate engineering effort and improving consistency.

**Agentic AI Engineering & Integration:**

- Hands-on, day-to-day use of AI coding agents such as GitHub Copilot, Claude, Cursor, Devin, and Factory to accelerate engineering delivery.

- Design and implement Agentic AI and RAG solutions using LangChain, LangGraph, LangSmith, MCP, and advanced Prompt Engineering techniques.

- Build multi-agent orchestration workflows using LangGraph patterns such as supervisor-worker, specialized agents, tool calling, state management, and workflow coordination.

- Design and integrate MCP servers to provide secure, governed access to enterprise tools, APIs, metadata, data platforms, and business services.

- Develop RAG-based agent capabilities integrating enterprise data, metadata, vector stores, and governed knowledge sources.

- Engineer agents as containerized, API-enabled microservices, integrating them with enterprise cloud platforms and existing data engineering workflows.

- Implement agent observability, tracing, evaluation, testing, and monitoring using LangSmith and related enterprise observability capabilities.

- Establish technical controls for agent security, authentication, authorization, human-in-the-loop, auditability, error handling, and responsible AI.

**Healthcare Domain Data Expertise:**

- Strong understanding of patient and Patient Management Services data, including patient journeys, enrollment, access, services, and interactions.

- Knowledge of related clinical, commercial, market access, and real-world healthcare data domains.

- Experience integrating and governing patient data across Salesforce, Data Lake/Lakehouse, analytics, and downstream platforms.

- Ensure patient data solutions meet data quality, security, privacy, lineage, GxP, HIPAA, GDPR, and enterprise governance requirements.

**Innovation & Continuous Improvement:**

- Drive technical innovation across the Data Lake and Salesforce PMP ecosystem using GenAI, Agentic AI, Conversational AI, and intelligent automation.

- Develop AI agents for metadata discovery, impact analysis, schema mapping, data quality diagnostics, pipeline monitoring, failure remediation, and operational support.

- Evaluate and integrate emerging capabilities such as MCP, LangGraph, LangChain, RAG, vector databases, Salesforce Agentforce, and Databricks AI services.

- Identify opportunities to modernize bidirectional Salesforce PMP and Data Lake integrations through event-driven processing, CDC, automated reconciliation, API orchestration, and near-real-time data synchronization.

- Build reusable technical accelerators for Salesforce object onboarding, Apex/API integration, schema-change detection, automated testing, and deployment automation.

- Convert successful POCs into secure, governed, observable, and production-ready enterprise capabilities that can be reused across patient and commercial data teams.

**Forward Deployed Engineering (FDE) & Solution Enablement:**

- Partner directly with Patient Management Services, Salesforce, Data Lake, product, and engineering teams to translate complex patient-services requirements into production-ready technical solutions.

- Lead rapid discovery and prototyping across Salesforce Apex, REST/Bulk APIs, SOQL, platform events, ADF, Databricks, Delta Lake, Unity Catalog, and downstream data products.

- Design and validate end-to-end Salesforce PMP-to-Data Lake and Data Lake-to-PMP data flows, including authentication, orchestration, transformation, synchronization, and downstream consumption.

- Resolve complex integration challenges involving API limits, high-volume processing, schema evolution, duplicate records, retries, idempotency, reconciliation, error handling, and data recovery.

- Build technical prototypes and reference implementations for GenAI, RAG, multi-agent orchestration, MCP-based tool access, and AI-enabled patient-services use cases.

- Embed production controls covering security, consent and privacy, PHI/PII protection, data quality, observability, auditability, performance, and operational readiness.

- Perform end-to-end impact analysis for Salesforce PMP changes across objects, fields, Apex services, APIs, Data Lake pipelines, data models, extracts, reports, and downstream consumers.

**Required skills:**

- 10+ years of data engineering/platform experience, including significant technical leadership at Senior/Principal Engineer level.

- Deep hands-on expertise across Azure, Databricks and enterprise Data Lakehouse platforms, including Spark/PySpark, Delta Lake, Apache Iceberg , streaming, Unity Catalog, ADF, ADLS, Key Vault, and Azure integration services.

- Proven experience designing enterprise-scale, metadata-driven ingestion and engineering capabilities, including batch, incremental, CDC, API, real-time processing, data quality, observability, and automated controls.

- Strong hands-on knowledge of the Salesforce ecosystem, including Apex, SOQL, REST/Bulk APIs, authentication, integration patterns, and bidirectional Salesforce-to-Data Lake integrations.

- Hands-on experience building GenAI and Agentic AI solutions using MCP, LangGraph, LangChain, RAG, Prompt Engineering, multi-agent orchestration, and related LLM technologies.

- Demonstrated day-to-day use of AI coding agents to accelerate and automate development, testing, code review, documentation, impact analysis, PR creation, and engineering workflows.

- Strong understanding of patient and healthcare data, with exposure to related clinical, commercial, market access, or real-world data domains.

- Experience with Infrastructure-as-Code, Git, CI/CD, automated testing, JIRA, ServiceNow, and modern DevOps practices.

- Excellent technical leadership and stakeholder management, with the ability to drive complex solutions across business, Salesforce, data, platform, architecture, security, and engineering teams.

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## Skills

### Required
- Azure
- Databricks
- Data Lakehouse
- Spark/PySpark
- Delta Lake
- Apache Iceberg
- Unity Catalog
- ADF
- ADLS
- Key Vault
- Salesforce
- Apex
- SOQL
- REST/Bulk APIs
- Agentic AI
- GenAI
- LangChain
- LangGraph
- MCP
- Prompt Engineering
- Infrastructure-as-Code
- Git
- CI/CD
- JIRA
- ServiceNow
- DevOps

### Nice to have
- Agentic AI architectures
- multi-agent orchestration
- MCP servers
- RAG
- agent observability/evaluation
- Responsible AI controls
- semantic models
- vector databases
- knowledge graphs
- data contracts
- metadata management
- advanced enterprise integration patterns
- MLOps
- AI/ML lifecycle management

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Source: [Apply at gsk.wd5.myworkdayjobs.com](https://gsk.wd5.myworkdayjobs.com/en-US/GSKCareers/job/Bengaluru-Luxor-North-Tower/Senior-Principal-Engineer--Data_448760?utm_source=yubhub.co&utm_medium=jobs_feed&utm_campaign=apply)
