# Postdoctoral Researcher, Horns Lab

**Company**: Arc Institute
**Location**: Palo Alto, CA
**Work arrangement**: onsite
**Experience**: senior
**Job type**: full-time
**Salary**: $80,000
**Category**: Research
**Industry**: Healthcare

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## Description

Arc Institute is an independent nonprofit research organization at the interface of artificial intelligence and biology, working to accelerate scientific progress and understand the root causes of complex diseases.

The Horns Lab is seeking motivated, hard-working, and curious scientists. Our lab develops and applies technologies that bridge synthetic biology and genomics to answer fundamental and translational questions in human health, with a particular emphasis on immunology and neuroscience.

As a Postdoctoral Researcher in the Horns Lab, you will conduct high-impact research, design, execute, and analyze experiments, and take end-to-end ownership of a research project within the lab's scientific focus, with guidance from the PI and increasing independence as you develop expertise.

Responsibilities:

- Conduct high-impact research: Design, execute, and analyze experiments;

- Develop as a future scientific leader: Publish first-author papers in high-impact journals, present at national and international conferences, and build a network of collaborators across Arc, Stanford, and beyond;

- Foster scientific excellence: Mentor and train research associates, technicians, and students;

Requirements:

- Doctorate (PhD, MD, MD/PhD, DVM, or equivalent) in bioengineering, synthetic biology, genomics, immunology, neuroscience, molecular biology, or a related field;

- Excellent written and verbal communication skills, including a track record of scientific writing (manuscripts, preprints, or equivalent);

- Demonstrated ability to work in a fast-paced environment and be both an independent thinker and a highly collaborative team player;

Preferred Qualifications:

- Experience in one or more of the following is a plus:

- Single-cell sequencing and analysis (scRNA-seq, scATAC-seq, CITE-seq)

- Spatial transcriptomics and multi-omics

- Pooled perturbation screens (CRISPRi/a/KO, Perturb-seq)

- Building new sequencing-based assays or new measurement modalities

- Molecular engineering (e.g. protein design and engineering)

- Mammalian synthetic biology (e.g. genetic circuit design)

- High-throughput library design and screening in mammalian cells

- Immune cell biology or engineering

- Immune receptor biology and profiling

- Neurobiology

- EVs, VLPs, or related nanoparticle systems

- In vivo models (e.g. mouse)

- Expertise in analysis of high-dimensional datasets (e.g. single-cell transcriptomics, spatial transcriptomics, pooled screening, using Python or R)

Benefits:

- The minimum base salary for this position is $80,000.

## Skills

### Required
- synthetic biology
- genomics
- immunology
- neuroscience
- bioengineering

### Nice to have
- single-cell sequencing
- spatial transcriptomics
- pooled perturbation screens
- molecular engineering
- immune cell biology
- neurobiology

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