# Senior Director, Cardiovascular and Metabolic Diseases, Clinical Pharmacology Modeling and Simulation

**Company**: GSK
**Location**: Massachusetts - Waltham
**Experience**: senior
**Job type**: full-time
**Salary**: $222,750 to $371,250
**Category**: Healthcare
**Industry**: Healthcare

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## Description

The Senior Director, Cardiovascular and Metabolic Diseases, Clinical Pharmacology Modeling and Simulation will lead the end-to-end application of Model-Informed Drug Development (MIDD) across the drug development lifecycle.

The role sits within the newly established Clinical Pharmacology and Quantitative Medicine (CPQM) organisation, which aims to be a centre of excellence in MIDD by integrating clinical pharmacology, digital medicine, translational imaging, and mechanistic/systems modelling.

Main responsibilities and accountabilities include:

- Design and execute Model Informed and Clinical Pharmacology strategies

- Coordinate and optimize CPMS activities across and above assets within RIIRU

- Ensure robust ways of working and regulatory-ready evidence

- Build cross-functional partnerships

- External engagement and scientific leadership

The ideal candidate will have a PhD, MD, or PharmD, 8+ years of industry experience in clinical pharmacology, modelling/simulation, and drug development, and experience in pharmacometrics and its application to clinical questions in drug development.

The salary range for this position is $222,750 to $371,250 per year, depending on location and experience. The company offers a comprehensive benefits program, including health care and other insurance benefits, retirement benefits, paid holidays, vacation, and paid caregiver/parental and medical leave.

## Skills

### Required
- Drug Design
- Drug Development
- Drug Discovery Process
- Medication Safety
- Molecular Modeling
- Pharmaceutical Regulatory Compliance
- Pharmaceutical Sciences
- Pharmacodynamics
- Pharmacokinetics
- Pharmacology
- Pharmacometrics
- Pharmacovigilance
- Study Design
- Target Validation

### Nice to have
- Demonstrated experience of collaboration in a multi-discipline team
- Evidenced experience making sound judgement in complex situations
- Strong track record of implementation of Model-Informed Drug Discovery and Development (MIDD) approaches

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