# Scientist I, Display Technologies

**Company**: Bighatbiosciences
**Location**: San Mateo, CA
**Work arrangement**: onsite
**Experience**: entry
**Job type**: full time
**Salary**: $120,000 - $145,000
**Category**: Laboratory Science
**Industry**: Healthcare

**Apply**: https://bighatbiosciences.pinpointhq.com/en/postings/f343b5b0-e798-4752-80c3-afa6e608bdc2?utm_source=yubhub.co&utm_medium=jobs_feed&utm_campaign=apply
**Canonical**: https://yubhub.co/jobs/job_08fd9eec-7da

## Description

BigHat Biosciences is seeking a Scientist 1 to join the Display Technologies team. The successful candidate will contribute to antibody discovery and engineering efforts, generating high-quality data to improve machine learning models.

## Key Responsibilities

- Support R&D projects advancing display technologies to expand antibody discovery capabilities and feed machine learning models.

- Construct and quality control phage display libraries across diverse antibody formats using standard molecular biology techniques.

- Execute standard phage display selections to engineer antibodies with desired therapeutic properties.

- Express, purify, and characterise display-derived molecules using various assays.

- Analyse selection results and contribute to discussions on next steps and future experimental design.

- Collaborate with Data Science and Machine Learning teams to inform library design and interpret selection data.

- Present experimental plans and results during regular meetings.

- Maintain thorough records using LIMS and electronic notebooks.

## Skills, Knowledge & Expertise

- PhD in Biochemistry, Structural Biology, Protein Engineering, or a related field, with up to 2 years of industry research experience; or an MS in a related field with 6+ years of relevant industry research experience.

- Experience with display technologies, including library design and selection strategies.

- Knowledge of antibody biology and protein expression.

- Strength in general molecular biology techniques.

- Nice-to-haves include experience with flow cytometry, ELISA, or other binding assays, and familiarity with NGS or automation platforms.

- Demonstrated ability to follow protocols carefully, troubleshoot experiments, and maintain detailed lab records.

- Effective time management and clear written and verbal communication skills.

- Collaborative, team-oriented mindset with an eagerness to learn in a fast-paced startup environment.

- Scientific track record and publication record.

- Strong data analysis and interpretation skills.

## Benefits

The salary estimated for this position is $120,000 - $145,000 + bonus + options + benefits.

## Skills

### Required
- PhD in Biochemistry
- Structural Biology
- Protein Engineering
- molecular biology techniques
- display technologies
- antibody biology
- protein expression

### Nice to have
- flow cytometry
- ELISA
- NGS
- automation platforms

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Source: [Apply at bighatbiosciences.pinpointhq.com](https://bighatbiosciences.pinpointhq.com/en/postings/f343b5b0-e798-4752-80c3-afa6e608bdc2?utm_source=yubhub.co&utm_medium=jobs_feed&utm_campaign=apply)