# Research Scientist- mIF experience

**Company**: ICON
**Location**: Cambridge, MA
**Work arrangement**: onsite
**Experience**: senior
**Job type**: full-time
**Salary**: $68,616.00-$85,770.00
**Category**: Research
**Industry**: Healthcare

**Apply**: https://icon.wd3.myworkdayjobs.com/en-US/broadbean_external/job/US-Cambridge-MA/Research-Scientist_JR156297?utm_source=yubhub.co&utm_medium=jobs_feed&utm_campaign=apply
**Canonical**: https://yubhub.co/jobs/job_05431ee2-cdb

## Description

ICON is seeking a Research Scientist to join their team in Cambridge, MA. As a Research Scientist at ICON, you will play a crucial role in designing, conducting, and analyzing complex clinical research studies.

Responsibilities:

- Develop, optimize, and apply quantitative image analysis workflows for multiplex immunofluorescence (mIF), tissue biomarker, and spatial biology studies.

- Collaborate with pathologists, bioinformaticians, and project teams to translate image analysis findings into actionable biological and biomarker insights.

- Design, develop, optimize, and perform mIF assays, including tissue staining and multispectral imaging of FFPE tissue samples, using platforms such as Akoya Biosciences (Phenoptics/PhenoImager), Leica Bond RX, or similar technologies.

- Assist in the optimization of antibody panels, fluorophore selection, and staining protocols to support assay performance and reproducibility.

- Maintain accurate experimental records and ensure data integrity in accordance with laboratory procedures and quality standards.

- Prepare and review technical reports, data summaries, presentations, and study documentation.

- Support assay qualification, validation, and implementation activities as needed.

- Contribute to SOP development and continuous process improvement initiatives.

- Stay current with emerging technologies and scientific advancements in multiplex immunofluorescence, digital pathology, and spatial biology.

- Present scientific findings at internal meetings and contribute to external publications and presentations, as appropriate.

- Support laboratory operations, including instrument maintenance, troubleshooting, performance monitoring, and coordination of service activities for tissue staining, imaging, and digital pathology platforms

Preferred Experience:

- Experience using Visiopharm to develop, optimize, and apply quantitative image analysis workflows for mIF and spatial biology studies.

- Experience interpreting image analysis results to generate biologically meaningful insights that support translational research and clinical biomarker studies.

- Familiarity with tumor immunology, immune profiling, and tissue biomarker characterization.

- Experience with digital pathology and whole-slide image management platforms such as Concentriq LS, or equivalent systems.

- Experience working in a GLP, GCLP, CLIA, or similarly regulated laboratory environment.

Qualifications:

- B.S., M.S., or Ph.D. in a life science or related discipline with relevant experience in multiplex immunofluorescence, digital pathology, spatial biology, image analysis, or tissue-based biomarker assays.

- Experience with automated staining platforms such as Leica Bond RX, Ventana Discovery Ultra, or equivalent systems.

- Experience with multispectral or fluorescence imaging platforms such as Akoya PhenoImager/Vectra Polaris, Zeiss, Olympus, or similar systems.

- Proficiency in digital pathology and image analysis software, including Visiopharm, HALO, QuPath, inForm, or equivalent platforms.

- Strong analytical, problem-solving, organizational, and communication skills.

- Ability to work independently while contributing effectively within a collaborative team environment.

Rewards & Benefits:

- Competitive base salary and performance related incentives

- Health and wellbeing programmes including medical, dental, and vision coverage where applicable

- Retirement and pension plans

- Life assurance and disability coverage

- Employee assistance programmes and wellbeing resources

- Learning and development opportunities through structured training and career pathways

## Skills

### Required
- multiplex immunofluorescence
- digital pathology
- spatial biology
- image analysis
- tissue-based biomarker assays
- Visiopharm
- HALO
- QuPath
- inForm

### Nice to have
- tumor immunology
- immune profiling
- tissue biomarker characterization
- Concentriq LS
- GLP
- GCLP
- CLIA

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